Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.52 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9330868 | 0.89 | PTPN11 (0.56) | KDM4EPTPN11ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7330160 | 0.89 | PTPN11 (0.56) | KDM4EPTPN11ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL9677245 | 0.89 | PTPN11 (0.56) | KDM4EPTPN11ALDH1A1SMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL9723762 | 0.88 | PTPN11 (0.55) | KDM4EPTPN11ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL3975419 | 0.80 | KDM4E (0.53) | KDM4EPTPN11ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL11517468 | 0.80 | TSHR (0.50) | ALDH1A1MEN1NR1I2LMNACHRM2 | |
| SCHEMBL9715200 | 0.80 | ADRB2 (0.61) | KDM4EPTPN11ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5969665 | 0.80 | ADRB2 (0.61) | KDM4EPTPN11ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL3826240 | 0.80 | ADRB2 (0.61) | KDM4EPTPN11ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL13739675 | 0.80 | ADRB2 (0.61) | KDM4EPTPN11ALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114613-A | High-speed responsive, stable films; controlling the mesomorphic state and temperature | CANON KABUSHIKI KAISHA (JP) | 1992-05-19 | — | — | US | disclosed |
| EP-0354355-A1 | Optically active compound and liquid crystal composition | MITSUBISHI RAYON CO., LTD. (JP) | 1990-02-14 | — | — | EP | disclosed |
| US-4882085-A | Lactic acid derivative and liquid crystal composition containing same | CANON KABUSHIKI KAISHA (JP) | 1989-11-21 | — | — | US | disclosed |