Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9677809 | 0.85 | MAPT (0.44) | SIGMAR1 | |
| SCHEMBL11148022 | 0.83 | NAAA (0.47) | NAAASIGMAR1FAAHMEN1KMT2A | |
| SCHEMBL11150214 | 0.76 | DPP4 (0.41) | NAAASIGMAR1S1PR5S1PR1MEN1 | |
| SCHEMBL11147047 | 0.76 | ESR1 (0.36) | SIGMAR1MEN1KMT2A | |
| SCHEMBL11145753 | 0.76 | CYP19A1 (0.47) | SIGMAR1 | |
| SCHEMBL11156844 | 0.72 | LTA4H (0.46) | LTA4HSIGMAR1 | |
| SCHEMBL5426458 | 0.71 | SIGMAR1 (0.52) | SIGMAR1MC4R | |
| SCHEMBL3882752 | 0.70 | S1PR5 (0.56) | CNR2LTA4HS1PR5HRH3FAAH | |
| SCHEMBL11146404 | 0.70 | KDM4E (0.46) | SIGMAR1MEN1KMT2A | |
| SCHEMBL15709181 | 0.70 | SIGMAR1 (0.55) | SIGMAR1MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4410532-A | N-Substituted aziridine-2-carboxylic acid derivatives and their immuno-stimulation compositions and methods | BOEHRINGER MANNHEIM GMBH (DE) | 1983-10-18 | — | — | US | disclosed |
| US-4409236-A | N-Substituted aziridine-2-carboxylic acid derivatives and immuno-stimulation composition and method | BOEHRINGER MANNHEIM GMBH (DE) | 1983-10-11 | — | — | US | disclosed |
| US-4321194-A | N-Substituted aziridine-2-carboxylic acid derivatives for immuno stimulation | BOEHRINGER MANNHEIM GMBH (DE) | 1982-03-23 | — | — | US | disclosed |