Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 8/20 | 0.51 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.50 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.50 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 2/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL620243 | 0.80 | PDK1 (0.58) | EPHX1PDK1PDK2PDK3PDK4 | |
| SCHEMBL14114344 | 0.79 | PDK1 (0.56) | EPHX1PDK1PDK2PDK3PDK4 | |
| SCHEMBL25482161 | 0.77 | EPHX1 (0.60) | EPHX1PDK1PDK2PDK3PDK4 | |
| SCHEMBL25482270 | 0.77 | EPHX1 (0.60) | EPHX1PDK1PDK2PDK3PDK4 | |
| SCHEMBL9611268 | 0.74 | PDK1 (0.63) | EPHX1PDK1PDK2PDK3PDK4 | |
| SCHEMBL18654098 | 0.74 | PDK1 (0.63) | EPHX1PDK1PDK2PDK3PDK4 | |
| SCHEMBL23481547 | 0.74 | PDK1 (0.63) | EPHX1PDK1PDK2PDK3PDK4 | |
| SCHEMBL18909861 | 0.73 | CCR2 (0.50) | EPHX1PDK1PDK2PDK3PDK4 | |
| SCHEMBL21555610 | 0.73 | CCR2 (0.51) | EPHX1PDK1PDK2PDK3PDK4 | |
| SCHEMBL20442986 | 0.72 | POLB (0.40) | EPHX1EPHX2ALDH1A1CCR2CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0513285-A1 | IMIDAZOL-2-YL DERIVATIVES OF SUBSTITUTED BICYCLIC COMPOUNDS AND PROCESS FOR THEIR PREPARATION. | ERBA CARLO SPA (IT) | 1992-11-19 | — | — | EP | disclosed |