Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.56 |
| ▸ | KIF11 | P52732 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9679224 | 0.90 | RIPK1 (0.54) | RIPK1KIF11GAACACNA1HLMNA | |
| SCHEMBL9678615 | 0.88 | RIPK1 (0.57) | RIPK1KIF11GAACACNA1HLMNA | |
| SCHEMBL9678604 | 0.87 | RIPK1 (0.56) | RIPK1KIF11GAACACNA1HLMNA | |
| SCHEMBL9678631 | 0.87 | RIPK1 (0.56) | RIPK1KIF11GAACACNA1HLMNA | |
| SCHEMBL9678856 | 0.85 | P2RY12 (0.42) | RIPK1GAACNR1P2RY12HTR6 | |
| SCHEMBL9676881 | 0.85 | RIPK1 (0.59) | RIPK1KIF11GAACACNA1HLMNA | |
| SCHEMBL9676962 | 0.85 | KIF11 (0.44) | RIPK1KIF11CNR1EGFRHTR6 | |
| SCHEMBL9676811 | 0.84 | RIPK1 (0.56) | RIPK1GAACACNA1HLMNATERT | |
| SCHEMBL9676048 | 0.84 | RIPK1 (0.56) | RIPK1KIF11GAACACNA1HLMNA | |
| SCHEMBL9676168 | 0.82 | RIPK1 (0.51) | RIPK1KIF11GAACACNA1HLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269141-B1 | 1-CARBAMOYL-2-PYRAZOLINE DERIVATIVES HAVING HERBICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1992-09-16 | — | — | EP | disclosed |
| US-4927452-A | 1-carbonyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1990-05-22 | — | — | US | disclosed |
| EP-0269141-A2 | 1-Carbamoyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1988-06-01 | — | — | EP | disclosed |