Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.56 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9676937 | 0.89 | RIPK1 (0.53) | RIPK1CACNA1HGAAKIF11LMNA | |
| SCHEMBL9678615 | 0.88 | RIPK1 (0.57) | RIPK1CACNA1HGAAKIF11LMNA | |
| SCHEMBL9678365 | 0.87 | RIPK1 (0.56) | RIPK1CACNA1HGAAKIF11LMNA | |
| SCHEMBL9678631 | 0.87 | RIPK1 (0.56) | RIPK1CACNA1HGAAKIF11LMNA | |
| SCHEMBL9676048 | 0.86 | RIPK1 (0.56) | RIPK1CACNA1HGAAKIF11LMNA | |
| SCHEMBL9676881 | 0.85 | RIPK1 (0.59) | RIPK1CACNA1HGAAKIF11LMNA | |
| SCHEMBL9677317 | 0.85 | KIF11 (0.42) | RIPK1CACNA1HKIF11LMNANT5E | |
| SCHEMBL9676811 | 0.84 | RIPK1 (0.56) | RIPK1CACNA1HGAALMNAALDH1A1 | |
| SCHEMBL9678597 | 0.83 | RIPK1 (0.53) | RIPK1CACNA1HGAAKIF11LMNA | |
| SCHEMBL9677340 | 0.83 | RIPK1 (0.50) | RIPK1CACNA1HGAAKIF11LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269141-B1 | 1-CARBAMOYL-2-PYRAZOLINE DERIVATIVES HAVING HERBICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1992-09-16 | — | — | EP | disclosed |
| US-4927452-A | 1-carbonyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1990-05-22 | — | — | US | disclosed |
| EP-0269141-A2 | 1-Carbamoyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1988-06-01 | — | — | EP | disclosed |