Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 10/20 | 0.49 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9678709 | 0.91 | HTR6 (0.45) | HTR6STSRIPK1MAPTMEN1 | |
| SCHEMBL9677350 | 0.87 | HTR6 (0.50) | HTR6ALDH1A1POLBGAA | |
| SCHEMBL9677235 | 0.84 | HTR6 (0.44) | HTR6STSRIPK1MAPTMEN1 | |
| SCHEMBL9676475 | 0.80 | POLB (0.59) | HTR6RIPK1MAPTMEN1ALDH1A1 | |
| SCHEMBL9677207 | 0.79 | HTR6 (0.38) | HTR6 | |
| SCHEMBL9678653 | 0.79 | HTR6 (0.46) | HTR6ALDH1A1POLBGAA | |
| SCHEMBL9677211 | 0.78 | RECQL (0.38) | HTR6RIPK1MAPTPOLB | |
| SCHEMBL9678578 | 0.77 | HTR6 (0.49) | HTR6STSATMSLC1A3SLC1A2 | |
| SCHEMBL9676134 | 0.76 | CA1 (0.42) | MAPTMEN1ALDH1A1KMT2APOLB | |
| SCHEMBL9677819 | 0.76 | ALKBH2 (0.41) | MEN1ALDH1A1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269141-B1 | 1-CARBAMOYL-2-PYRAZOLINE DERIVATIVES HAVING HERBICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1992-09-16 | — | — | EP | disclosed |
| US-4927452-A | 1-carbonyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1990-05-22 | — | — | US | disclosed |
| EP-0269141-A2 | 1-Carbamoyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1988-06-01 | — | — | EP | disclosed |