Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.56 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7999499 | 0.82 | CHRNB2 (0.54) | CHRNB2CHRNA4ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL14993193 | 0.81 | ALDH1A1 (0.53) | MEN1KMT2AMAPTCHRNB2CHRNA4 | |
| SCHEMBL152680 | 0.80 | MAPT (0.70) | POLBMEN1KMT2AMAPTCYP2C9 | |
| SCHEMBL5251522 | 0.80 | MAPT (0.70) | POLBMEN1KMT2AMAPTCYP2C9 | |
| Hydrochloric Acid SCHEMBL1306753 | 0.80 | ALDH1A1 (0.52) | MEN1KMT2AMAPTCHRNB2CHRNA4 | |
| SCHEMBL9677155 | 0.79 | POLB (0.66) | POLBMEN1KMT2AMAPTCYP2C9 | |
| SCHEMBL26092460 | 0.78 | CHRNB2 (0.50) | POLBCHRNB2CHRNA4ALDH1A1KDM4E | |
| SCHEMBL30910100 | 0.78 | CHRNB2 (0.50) | POLBCHRNB2CHRNA4ALDH1A1KDM4E | |
| SCHEMBL1307367 | 0.78 | CHRNB2 (0.58) | MAPTCHRNB2CHRNA4ALDH1A1KDM4E | |
| SCHEMBL6791963 | 0.78 | ALDH1A1 (0.49) | MEN1KMT2AMAPTCHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268229-B1 | IMIDAZOLIDINONE COMPOUNDS, PROCESSES FOR PREPARATION THEREOF, COMPOSITIONS COMPRISING SUCH COMPOUNDS, AND THE USE OF SUCH COMPOUNDS FOR THE MANUFACTURE OF MEDICAMENTS HAVING THERAPEUTIC VALUE | TANABE SEIYAKU CO., LTD. (JP) | 1992-07-08 | — | — | EP | disclosed |
| US-4886817-A | Imidazolidinones as brain activators | TANABE SEIYAKU CO., LTD. (JP) | 1989-12-12 | — | — | US | disclosed |
| EP-0268229-A2 | Imidazolidinone compounds, processes for preparation thereof, compositions comprising such compounds, and the use of such compounds for the manufacture of medicaments having therapeutic value | TANABE SEIYAKU CO., LTD. (JP) | 1988-05-25 | — | — | EP | disclosed |