Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8658341 | 0.81 | DAO (0.44) | ALDH1A1CHRNB2CHRNA4HTTMAPK1 | |
| SCHEMBL22144492 | 0.80 | EPHX2 (0.47) | ALDH1A1EPHX2OPRM1DDB1CRBN | |
| SCHEMBL9850086 | 0.80 | DDB1 (0.69) | ALDH1A1EPHX2DDB1CRBNGAA | |
| SCHEMBL1011633 | 0.80 | DDB1 (0.69) | ALDH1A1EPHX2DDB1CRBNGAA | |
| SCHEMBL9850110 | 0.78 | DDB1 (0.67) | ALDH1A1EPHX2DDB1CRBNMAPK1 | |
| SCHEMBL9678558 | 0.78 | POLB (0.56) | ALDH1A1CHRNB2CHRNA4HTTMAPK1 | |
| SCHEMBL1307367 | 0.73 | CHRNB2 (0.58) | ALDH1A1CHRNB2CHRNA4HTTOPRM1 | |
| SCHEMBL14993193 | 0.73 | ALDH1A1 (0.53) | ALDH1A1CHRNB2CHRNA4HTTOPRM1 | |
| SCHEMBL5182904 | 0.72 | EPHX2 (0.47) | EPHX2DDB1CRBNMAPK1MEN1 | |
| SCHEMBL7287505 | 0.72 | L3MBTL1 (0.58) | ALDH1A1CHRNB2CHRNA4HTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040242892-A1 | Method for synthesis of 5-(3-pyridylmethylene-)imidazolidine-2,4-dione | SOLVAY S.A. (BE) | 2004-12-02 | — | — | US | disclosed |
| JP-2003081971-A | 5-PYRIDYLMETHYLHYDANTOIN AND N-CARBAMOYL-3-(PYRIDYL) ALANINE | K I CHEMICAL INDUSTRY CO LTD | 2003-03-19 | — | — | JP | disclosed |
| JP-2003081970-A | 5-PYRIDYLMETHYLHYDANTOIN AND METHOD OF PRODUCING THE SAME | K I CHEMICAL INDUSTRY CO LTD | 2003-03-19 | — | — | JP | disclosed |
| EP-1083170-A1 | Method for producing D-(3'-Pyridyl)-alanine | Degussa-Hüls Aktiengesellschaft (DE) | 2001-03-14 | — | — | EP | disclosed |