Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.61 |
| ▸ | NPC1 | O15118 | 7/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.61 |
| ▸ | RELA | Q04206 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9678412 | 0.93 | RAB9A (0.56) | RAB9ANPC1SMN1; SMN2HPGDNFKB1 | |
| SCHEMBL6483534 | 0.86 | RAB9A (0.64) | RAB9ANPC1SMN1; SMN2HPGDNFKB1 | |
| SCHEMBL10478297 | 0.86 | SMN1; SMN2 (0.45) | RAB9ANPC1SMN1; SMN2HPGDNFKB1 | |
| SCHEMBL10703839 | 0.86 | SMN1; SMN2 (0.46) | RAB9ANPC1SMN1; SMN2HPGDNFKB1 | |
| SCHEMBL10701467 | 0.84 | CYP2E1 (0.56) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL10869688 | 0.83 | RAB9A (0.56) | RAB9ANPC1SMN1; SMN2HPGDNFKB1 | |
| SCHEMBL10701037 | 0.81 | CYP2E1 (0.48) | RAB9ANPC1SMN1; SMN2HPGDNFKB1 | |
| SCHEMBL3377470 | 0.80 | RAB9A (0.57) | RAB9ANPC1SMN1; SMN2HPGDNFKB1 | |
| SCHEMBL9675826 | 0.77 | NPC1 (0.53) | RAB9ANPC1SMN1; SMN2HPGDNFKB1 | |
| SCHEMBL12604487 | 0.76 | NPC1 (0.73) | RAB9ANPC1SMN1; SMN2HPGDNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0174717-B1 | BENZIMIDAZOLES, AND THEIR PRODUCTION FORMULATION AND USE AS GASTRIC ACID SECRETION INHIBITORS | FISONS plc (GB) | 1992-01-22 | — | — | EP | disclosed |
| EP-0174717-A1 | Benzimidazoles, and their production formulation and use as gastric acid secretion inhibitors | FISONS plc (GB) | 1986-03-19 | — | — | EP | disclosed |