Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | POLA1 | P09884 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | FPR1 | P21462 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10667584 | 1.00 | EHMT2 (0.38) | EHMT2KDM4ELMNAMMP1MMP3 | |
| SCHEMBL9679618 | 0.87 | EHMT2 (0.42) | EHMT2KDM4EMEN1KMT2APOLB | |
| SCHEMBL9737467 | 0.85 | EHMT2 (0.35) | EHMT2KDM4ELMNAMEN1KMT2A | |
| SCHEMBL9679741 | 0.78 | EHMT2 (0.46) | EHMT2MEN1KMT2APOLBHDAC6 | |
| SCHEMBL3084318 | 0.78 | EHMT2 (0.46) | EHMT2MEN1KMT2APOLBHDAC6 | |
| SCHEMBL3092207 | 0.76 | EHMT2 (0.44) | EHMT2MEN1KMT2APOLBFPR1 | |
| SCHEMBL9845295 | 0.74 | MEN1 (0.42) | EHMT2KDM4ELMNAMEN1KMT2A | |
| SCHEMBL9032586 | 0.74 | MEN1 (0.42) | EHMT2KDM4ELMNAMEN1KMT2A | |
| SCHEMBL9845296 | 0.74 | MEN1 (0.39) | EHMT2KDM4ELMNAMEN1KMT2A | |
| SCHEMBL6049147 | 0.70 | ALDH1A1 (0.53) | EHMT2MEN1KMT2APOLBPOLA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5095118-A | PROCESS FOR THE PREPARATION OF D-(+)-BIOTIN | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-03-10 | — | — | US | disclosed |
| EP-0242686-B1 | PROCESS FOR THE PREPARATION OF D-(+)-BIOTINE | MERCK PATENT GmbH (DE) | 1992-01-29 | — | — | EP | disclosed |
| US-4937351-A | Process for the preparation of D-(+)-biotin | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-06-26 | — | — | US | disclosed |
| US-4877882-A | Process for the preparation of D-(+)-biotin | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-10-31 | — | — | US | disclosed |
| US-4837402-A | Process for the preparation of D-(+)-biotin | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-06-06 | — | — | US | disclosed |
| US-4732987-A | Process for the preparation of D-(+)-biotin | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-03-22 | — | — | US | disclosed |
| EP-0242686-A2 | Process for the preparation of D-(+)-biotine | MERCK PATENT GmbH (DE) | 1987-10-28 | — | — | EP | disclosed |