⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5056726 | 0.71 | — | — | |
| SCHEMBL1673128 | 0.68 | — | — | |
| SCHEMBL28116569 | 0.67 | FBP1 (0.31) | — | |
| SCHEMBL2997274 | 0.67 | — | — | |
| SCHEMBL633330 | 0.65 | KDM4E (0.44) | — | |
| SCHEMBL27853360 | 0.65 | — | — | |
| SCHEMBL968554 | 0.65 | KDM4E (0.57) | — | |
| SCHEMBL8330113 | 0.65 | — | — | |
| SCHEMBL17028970 | 0.65 | KDM4E (0.33) | — | |
| SCHEMBL17476685 | 0.65 | TP53 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7871982-B2 | Lincomycin derivatives and antimicrobial agents comprising the same as active ingredient | MEIJI SEIKA KAISHA, LTD. (JP) | 2011-01-18 | — | — | US | claimed |
| US-20090156512-A1 | potent activity against resistant pneumococci | MEIJI SEIKA KAISHA, LTD. (JP) | 2009-06-18 | — | — | US | claimed |
| EP-1970377-A1 | LINCOMYCIN DERIVATIVE AND ANTIBACTERIAL AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2008-09-17 | — | — | EP | claimed |
| EP-2902026-A1 | THIAZOLIDINEDIONE ANALOGUES FOR THE TREATMENT OF METABOLIC INFLAMMATION MEDIATED DISEASE | Metabolic Solutions Development Company LLC (US) | 2015-08-05 | — | — | EP | disclosed |
| EP-2486926-A1 | Thiazolidinedione Analogues | Metabolic Solutions Development Company LLC (US) | 2012-08-15 | — | — | EP | disclosed |
| US-7871982-B2 | Lincomycin derivatives and antimicrobial agents comprising the same as active ingredient | MEIJI SEIKA KAISHA, LTD. (JP) | 2011-01-18 | — | — | US | disclosed |
| US-20090156512-A1 | potent activity against resistant pneumococci | MEIJI SEIKA KAISHA, LTD. (JP) | 2009-06-18 | — | — | US | disclosed |
| EP-2001468-A2 | THIAZOLIDINEDIONE ANALOGUES | Metabolic Solutions Development Company (US) | 2008-12-17 | — | — | EP | disclosed |
| EP-1970377-A1 | LINCOMYCIN DERIVATIVE AND ANTIBACTERIAL AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2008-09-17 | — | — | EP | disclosed |
| WO-2007109024-A2 | THIAZOLIDINEDIONE ANALOGUES FOR THE TREATMENT OF METABOLIC INFLAMMATION MEDIATED DISEASE | METABOLIC SOLUTIONS DEVELOPMENT COMPANY (US) | 2007-09-27 | — | — | WO | disclosed |