Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL996341 | 0.96 | TSHR (0.40) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL997848 | 0.85 | TSHR (0.39) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL19410597 | 0.85 | ALDH1A1 (0.45) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL1095965 | 0.85 | ALDH1A1 (0.45) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL14865749 | 0.85 | ALDH1A1 (0.41) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL19410608 | 0.85 | ALDH1A1 (0.45) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL19410575 | 0.85 | ALDH1A1 (0.45) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL475462 | 0.85 | ALDH1A1 (0.45) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL17358693 | 0.85 | ALDH1A1 (0.45) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL1094765 | 0.85 | ALDH1A1 (0.45) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169921-A | Composing branched propylene/1,2-/ segment of polyol for flexibility and adhesion at low temperature | DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) | 1992-12-08 | — | — | US | disclosed |
| EP-0498370-A2 | Polyurethane type curable coating composition | DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) | 1992-08-12 | — | — | EP | disclosed |