Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL138322 | 1.00 | ALDH1A1 (0.45) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL17358693 | 1.00 | ALDH1A1 (0.45) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL19410606 | 1.00 | ALDH1A1 (0.45) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL19410597 | 1.00 | ALDH1A1 (0.45) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL19410608 | 1.00 | ALDH1A1 (0.45) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL19410575 | 1.00 | ALDH1A1 (0.45) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL1094765 | 1.00 | ALDH1A1 (0.45) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL475462 | 1.00 | ALDH1A1 (0.45) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL40032 | 0.96 | ALDH1A1 (0.47) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 | |
| Ammonia Solution, Strong SCHEMBL28794546 | 0.94 | ALDH1A1 (0.46) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 252 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3602149-B1 | OPTICAL ARTICLE COMPRISING AN ABRASION- AND/OR SCRATCH-RESISTANT COATING HAVING A LOW SENSITIVITY TO CRACKS | ESSILOR INT (FR) | 2022-08-24 | — | — | EP | claimed |
| CN-110431451-B | Optical article comprising a wear-and/or scratch-resistant coating with low crack sensitivity | 依视路国际公司 | 2021-11-23 | — | — | CN | claimed |
| US-20200096674-A1 | Optical Article Comprising an Abrasion- and/or Scratch-Resistant Coating Having a Low Sensitivity to Cracks | ESSILOR INTERNATIONAL (FR) | 2020-03-26 | — | — | US | claimed |
| EP-3602149-A1 | OPTICAL ARTICLE COMPRISING AN ABRASION- AND/OR SCRATCH-RESISTANT COATING HAVING A LOW SENSITIVITY TO CRACKS | Essilor International (FR) | 2020-02-05 | — | — | EP | claimed |
| EP-3382429-A1 | OPTICAL ARTICLE COMPRISING AN ABRASION- AND/OR SCRATCH-RESISTANT COATING HAVING A LOW SENSITIVITY TO CRACKS | Essilor International (FR) | 2018-10-03 | — | — | EP | claimed |
| US-20260133349-A1 | EYEGLASS LENS AND EYEGLASSES | HOYA LENS THAILAND LTD. (TH) | 2026-05-14 | — | — | US | disclosed |
| US-20260117117-A1 | PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND EYEGLASSES | HOYA LENS THAILAND LTD. (TH) | 2026-04-30 | — | — | US | disclosed |
| EP-4733304-A2 | PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND EYEGLASSES | HOYA Lens Thailand Ltd. (TH) | 2026-04-29 | — | — | EP | disclosed |
| EP-4198102-B1 | PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND EYEGLASSES | HOYA LENS THAILAND LTD (TH) | 2026-04-01 | — | — | EP | disclosed |
| US-12577455-B2 | Photochromic compound, photochromic composition, photochromic article and spectacles | HOYA LENS THAILAND LTD. (TH) | 2026-03-17 | — | — | US | disclosed |
| US-20260042742-A1 | PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE AND EYEGLASSES | HOYA LENS THAILAND LTD. (TH) | 2026-02-12 | — | — | US | disclosed |
| EP-4674924-A1 | PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND EYEGLASSES | Hoya Lens Thailand Ltd. (TH) | 2026-01-07 | — | — | EP | disclosed |
| US-6057039-A | AS CURING CATALYSTS, IRON, ALUMINUM, TIN, OR TITANIUM ACETYLACETONATE DERIVATIVES AND MAGNESIUM PERCHLORATE OR AMMONIUM PERCHLORATE; AND ACETYLACETONATE DERIVATIVES OF LITHIUM, COPPER, MANGANESE; POT LIFE; EYEGLASS LENSE | SEIKO EPSON CORPORATION (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0939329-A1 | Eyeglass lenses for correcting color vision | SEIKO EPSON CORPORATION (JP) | 1999-09-01 | — | — | EP | disclosed |
| EP-0441383-B1 | Use of a copolymer for the making of contact lenses | MITSUBISHI RAYON CO (JP) | 1996-05-08 | — | — | EP | disclosed |
| EP-0430209-B1 | Resin composition for cast polymerization | MITSUBISHI RAYON CO (JP) | 1996-02-28 | — | — | EP | disclosed |
| US-5247038-A | Optical materials | MITSUBISHI RAYON CO., LTD. (JP) | 1993-09-21 | — | — | US | disclosed |
| US-5183870-A | A curable polybutylene glycol di(meth)acrylate, a urethane or epoxy (meth)acrylate and a (meth)acrylate; heat and water resistance; impact strength; dyeability; workability | MITSUBISHI RAYON CO., LTD (JP) | 1993-02-02 | — | — | US | disclosed |
| EP-0441383-A2 | Use of a copolymer for the making of contact lenses | MITSUBISHI RAYON CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
| EP-0430209-A2 | Resin composition for cast polymerization | MITSUBISHI RAYON CO., LTD. (JP) | 1991-06-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260042742-A1 | PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE AND EYEGLASSES | NR2E3, FRG1, ALDH1A2 | ALDH1A1 955/4885TSHR 377/4885MAPK1 1604/4885 |
| US-20260117117-A1 | PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND EYEGLASSES | NR2E3, ALDH1A2, RAD51 | ALDH1A1 657/4885TSHR 861/4885MAPK1 1455/4885 |
| US-20200096674-A1 | Optical Article Comprising an Abrasion- and/or Scratch-Resistant Coating Having a Low Sensitivity to Cracks | C9, PCNA, MSN | ALDH1A1 2479/4885TSHR 4583/4885MAPK1 1840/4885 |
| US-12577455-B2 | Photochromic compound, photochromic composition, photochromic article and spectacles | CRY1, HBG1, ALDH1A2 | ALDH1A1 126/4885TSHR 2400/4885MAPK1 1864/4885 |
| US-20260133349-A1 | EYEGLASS LENS AND EYEGLASSES | TLL1, GLUL, POT1 | ALDH1A1 3550/4885TSHR 753/4885MAPK1 2574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.