Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | CCR3 | P51677 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9675908 | 0.83 | POLB (0.47) | HTR6RIPK1MEN1RAB9AKMT2A | |
| SCHEMBL9677211 | 0.81 | RECQL (0.38) | HTR6RIPK1 | |
| SCHEMBL9677350 | 0.81 | HTR6 (0.50) | HTR6HRH1CCR3P2RY12ALDH1A1 | |
| SCHEMBL9677819 | 0.81 | ALKBH2 (0.41) | SLC22A12MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9676134 | 0.81 | CA1 (0.42) | MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9678669 | 0.79 | HTR6 (0.51) | HTR6 | |
| SCHEMBL9675912 | 0.77 | TERT (0.35) | SLC22A12NR1I2RIPK1ALDH1A1LMNA | |
| SCHEMBL9678966 | 0.75 | MAPT (0.37) | HTR6RIPK1MEN1KMT2ALMNA | |
| SCHEMBL9678583 | 0.75 | SLC22A12 (0.40) | HTR6SLC22A12HRH1CCR3RAB9A | |
| SCHEMBL9678650 | 0.74 | SLC22A12 (0.35) | SLC22A12HRH1CCR3NR1I2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269141-B1 | 1-CARBAMOYL-2-PYRAZOLINE DERIVATIVES HAVING HERBICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1992-09-16 | — | — | EP | disclosed |
| US-4927452-A | 1-carbonyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1990-05-22 | — | — | US | disclosed |
| EP-0269141-A2 | 1-Carbamoyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1988-06-01 | — | — | EP | disclosed |