Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MLYCD | O95822 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9679558 | 0.91 | SMN1; SMN2 (0.65) | SMN1; SMN2ALDH1A1TSHRMAPK1HRH3 | |
| SCHEMBL9679472 | 0.84 | ALDH1A1 (0.60) | SMN1; SMN2ALDH1A1TSHRMAPK1HRH3 | |
| SCHEMBL10940747 | 0.84 | SMN1; SMN2 (0.72) | SMN1; SMN2ALDH1A1TSHRMAPK1HRH3 | |
| SCHEMBL10941442 | 0.84 | ALDH1A1 (0.72) | SMN1; SMN2ALDH1A1TSHRMAPK1HRH3 | |
| SCHEMBL27630183 | 0.83 | ALDH1A1 (0.70) | SMN1; SMN2ALDH1A1TSHRMAPK1HRH3 | |
| SCHEMBL9291268 | 0.83 | ALDH1A1 (0.70) | SMN1; SMN2ALDH1A1TSHRMAPK1HRH3 | |
| SCHEMBL701448 | 0.83 | MAPK1 (0.70) | SMN1; SMN2ALDH1A1TSHRMAPK1HRH3 | |
| SCHEMBL9680431 | 0.82 | ALDH1A1 (0.58) | SMN1; SMN2ALDH1A1TSHRMAPK1HRH3 | |
| SCHEMBL727136 | 0.81 | ALDH1A1 (0.68) | SMN1; SMN2ALDH1A1TSHRMAPK1HRH3 | |
| SCHEMBL600821 | 0.81 | SMN1; SMN2 (0.68) | SMN1; SMN2ALDH1A1TSHRMAPK1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145885-A | Morpholine compound, binders | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |