SCHEMBL9679558

SCHEMBL9679558

CN(C)c1ccc(C(=O)C(C)(C)N2CCOCC2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.65
ALDH1A1 P00352 2/20 0.65
TSHR P16473 1/20 0.65
MAPK1 P28482 1/20 0.65
TP53 P04637 2/20 0.50
MEN1 O00255 1/20 0.50
GAA P10253 1/20 0.50
KMT2A Q03164 1/20 0.50
ESR2 Q92731 1/20 0.50
MAPT P10636 4/20 0.47
HRH3 Q9Y5N1 1/20 0.46
HPGD P15428 2/20 0.44
LMNA P02545 1/20 0.41
RAB9A P51151 4/20 0.40
NPC1 O15118 2/20 0.40
MLYCD O95822 2/20 0.39
HTT P42858 1/20 0.39
HIF1A Q16665 1/20 0.39
EPAS1 Q99814 1/20 0.39
HSP90AA1 P07900 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9679447 0.91 SMN1; SMN2 (0.65) SMN1; SMN2ALDH1A1TSHRMAPK1TP53
SCHEMBL9681616 0.85 ALDH1A1 (0.48) SMN1; SMN2ALDH1A1TSHRMAPK1TP53
SCHEMBL9679422 0.84 ALDH1A1 (0.47) SMN1; SMN2ALDH1A1TSHRMAPK1TP53
SCHEMBL9679472 0.84 ALDH1A1 (0.60) SMN1; SMN2ALDH1A1TSHRMAPK1TP53
SCHEMBL10941442 0.84 ALDH1A1 (0.72) SMN1; SMN2ALDH1A1TSHRMAPK1MAPT
SCHEMBL10940747 0.84 SMN1; SMN2 (0.72) SMN1; SMN2ALDH1A1TSHRMAPK1TP53
SCHEMBL9681282 0.83 ALDH1A1 (0.46) SMN1; SMN2ALDH1A1TSHRMAPK1TP53
SCHEMBL9681156 0.83 SMN1; SMN2 (0.55) SMN1; SMN2ALDH1A1TSHRMAPK1TP53
SCHEMBL701448 0.83 MAPK1 (0.70) SMN1; SMN2ALDH1A1TSHRMAPK1TP53
SCHEMBL9291268 0.83 ALDH1A1 (0.70) SMN1; SMN2ALDH1A1TSHRMAPK1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11833744-B2 Dual precursor resin systems for additive manufacturing with dual cure resins CARBON, INC. (US) 2023-12-05 US disclosed
US-11833744-B2 Dual precursor resin systems for additive manufacturing with dual cure resins CARBON, INC. (US) 2023-12-05 US disclosed
US-11707893-B2 Methods for producing three-dimensional objects with apparatus having feed channels CARBON, INC. (US) 2023-07-25 US disclosed
EP-4166332-A1 ADDITIVES USEFUL IN 3D PRINTING TECHNOLOGIES Evonik Operations GmbH (DE) 2023-04-19 EP disclosed
US-20230001634-A1 METHODS OF PRODUCING THREE-DIMENSIONAL OBJECTS WITH APPARATUS HAVING FEED CHANNELS CARBON INC (US) 2023-01-05 US disclosed
EP-3158399-B1 POLYURETHANE RESINS HAVING MULTIPLE MECHANISMS OF HARDENING FOR USE IN PRODUCING THREE-DIMENSIONAL OBJECTS CARBON INC (US) 2022-10-26 EP disclosed
US-20220203609-A1 DUAL PRECURSOR RESIN SYSTEMS FOR ADDITIVE MANUFACTURING WITH DUAL CURE RESINS CARBON INC (US) 2022-06-30 US disclosed
US-11358342-B2 Methods of producing three-dimensional objects from materials having multiple mechanisms of hardening CARBON, INC. (US) 2022-06-14 US disclosed
EP-3157722-B1 THREE-DIMENSIONAL OBJECTS PRODUCED FROM MATERIALS HAVING MULTIPLE MECHANISMS OF HARDENING CARBON INC (US) 2022-06-01 EP disclosed
EP-3158400-B1 METHODS OF PRODUCING THREE-DIMENSIONAL OBJECTS FROM MATERIALS HAVING MULTIPLE MECHANISMS OF HARDENING CARBON INC (US) 2022-06-01 EP disclosed
US-20100216065-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2010-08-26 US disclosed
US-20100216065-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2010-08-26 US disclosed
US-20100129115-A1 ORGANIC PHOTORECEPTOR, MANUFACTURING METHOD OF ORGANIC PHOTORECEPTOR, AND IMAGE FORMING APPARATUS KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2010-05-27 US disclosed
US-20100086328-A1 ORGANIC PHOTORECEPTOR, MANUFACTURING METHOD OF ORGANIC PHOTORECEPTOR, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2010-04-08 US disclosed
US-20100086328-A1 ORGANIC PHOTORECEPTOR, MANUFACTURING METHOD OF ORGANIC PHOTORECEPTOR, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2010-04-08 US disclosed
US-20090286175-A1 ORGANIC PHOTORECEPTOR, IMAGE FORMING APPARATUS, PROCESS CARTRIDGE, AND COLOR IMAGE FORMING APPARATUS KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2009-11-19 US disclosed
US-20090286175-A1 ORGANIC PHOTORECEPTOR, IMAGE FORMING APPARATUS, PROCESS CARTRIDGE, AND COLOR IMAGE FORMING APPARATUS KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2009-11-19 US disclosed
US-5145885-A Morpholine compound, binders CIBA-GEIGY CORPORATION (US) 1992-09-08 US disclosed
US-4992547-A Aminoaryl ketone photoinitiators CIBA-GEIGY CORPORATION (US) 1991-02-12 US disclosed
EP-0402932-A1 Photopolymerizable coating products OECE Industrie Chimiche Spa (IT) 1990-12-19 EP disclosed