Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.51 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | MLYCD | O95822 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4444933 | 0.81 | HPGD (1.00) | HPGDALDH1A1MAPTGAAL3MBTL1 | |
| SCHEMBL6247420 | 0.80 | HPGD (0.62) | HPGDALDH1A1MAPTGAAL3MBTL1 | |
| SCHEMBL5703500 | 0.78 | HPGD (0.73) | HPGDALDH1A1MAPTGAAL3MBTL1 | |
| SCHEMBL9679486 | 0.78 | SMN1; SMN2 (0.65) | HPGDALDH1A1MAPTGAAL3MBTL1 | |
| SCHEMBL6246322 | 0.78 | HPGD (0.59) | HPGDALDH1A1MAPTGAAL3MBTL1 | |
| SCHEMBL27523461 | 0.77 | HPGD (0.79) | HPGDALDH1A1MAPTGAAL3MBTL1 | |
| SCHEMBL72112 | 0.77 | HPGD (0.85) | HPGDALDH1A1MAPTGAAL3MBTL1 | |
| SCHEMBL6246739 | 0.75 | HSP90AA1 (0.56) | HPGDALDH1A1MAPTGAAL3MBTL1 | |
| SCHEMBL1806308 | 0.75 | HPGD (0.63) | HPGDALDH1A1MAPTL3MBTL1HSP90AA1 | |
| Hydrochloric Acid SCHEMBL6612619 | 0.75 | HPGD (0.81) | HPGDALDH1A1MAPTGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1256575-B1 | PHENOXYALKYLAMINE DERIVATIVES USEFUL AS OPIOID DELTA RECEPTOR AGONISTS | MEIJI SEIKA KAISHA (JP) | 2005-08-17 | — | — | EP | disclosed |
| US-6916822-B2 | Phenoxyalkylamine derivatives useful as opioid δ receptor agonists | MEIJI SEIKA KAISHA, LTD. (JP) | 2005-07-12 | — | — | US | disclosed |
| US-20050148583-A1 | Phenoxyalkylamine derivatives useful as opioid delta receptor ligands | MEIJI SEIKA KAISHA, LTD. (JP) | 2005-07-07 | — | — | US | disclosed |
| US-20030171370-A1 | Phenoxyalkylamine derivatives useful as opioid receptor agonists | MEIJI SEIKA KAISHA, LTD. (JP) | 2003-09-11 | — | — | US | disclosed |
| EP-1256575-A1 | PHENOXYALKYLAMINE DERIVATIVES USEFUL AS OPIOID DELTA RECEPTOR AGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2002-11-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030171370-A1 | Phenoxyalkylamine derivatives useful as opioid receptor agonists | OPRM1, OPRK1, OPRD1 | HPGD 2331/4885ALDH1A1 2141/4885MAPT 2335/4885 |
| US-20050148583-A1 | Phenoxyalkylamine derivatives useful as opioid delta receptor ligands | OPRD1, OPRM1, OPRK1 | HPGD 2802/4885ALDH1A1 1810/4885MAPT 2198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.