Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8900808 | 0.85 | ALDH1A1 (0.39) | ALDH1A1MAPK1SMN1; SMN2TSHRHRH3 | |
| SCHEMBL9679472 | 0.83 | ALDH1A1 (0.60) | ALDH1A1MAPK1SMN1; SMN2TSHRHRH3 | |
| SCHEMBL10458498 | 0.81 | ALDH1A1 (0.50) | ALDH1A1MAPK1SMN1; SMN2TSHRHRH3 | |
| SCHEMBL13342971 | 0.80 | ALDH1A1 (0.36) | ALDH1A1MAPK1SMN1; SMN2TSHRHRH3 | |
| SCHEMBL9679558 | 0.79 | SMN1; SMN2 (0.65) | ALDH1A1MAPK1SMN1; SMN2TSHRHRH3 | |
| SCHEMBL9679447 | 0.79 | SMN1; SMN2 (0.65) | ALDH1A1MAPK1SMN1; SMN2TSHRHRH3 | |
| SCHEMBL9680431 | 0.79 | ALDH1A1 (0.58) | ALDH1A1MAPK1SMN1; SMN2TSHRHRH3 | |
| SCHEMBL3677741 | 0.78 | ALDH1A1 (0.60) | ALDH1A1MAPK1SMN1; SMN2TSHRHRH3 | |
| SCHEMBL18883182 | 0.77 | ALDH1A1 (0.63) | ALDH1A1MAPK1SMN1; SMN2TSHRHRH3 | |
| SCHEMBL10456895 | 0.77 | HRH3 (0.68) | ALDH1A1MAPK1SMN1; SMN2TSHRHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145885-A | Morpholine compound, binders | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| US-4960746-A | A-HYDROXY-OR A-AMINO-ACETOPHENONES AND A TITANOCENE COMPOUND SUBSTITUTED BY FLUORINE | CIBA-GEIGY CORPORATION (US) | 1990-10-02 | — | — | US | disclosed |