Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | TSHR | P16473 | 2/20 | 0.72 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10884364 | 0.94 | ALDH1A1 (0.81) | SMN1; SMN2MAPK1ALDH1A1TSHRRAB9A | |
| SCHEMBL10889886 | 0.94 | ALDH1A1 (0.81) | SMN1; SMN2MAPK1ALDH1A1TSHRRAB9A | |
| SCHEMBL701448 | 0.91 | MAPK1 (0.70) | SMN1; SMN2MAPK1ALDH1A1TSHRRAB9A | |
| SCHEMBL28995353 | 0.90 | SMN1; SMN2 (0.89) | SMN1; SMN2MAPK1ALDH1A1TSHRRAB9A | |
| SCHEMBL1553588 | 0.89 | ALDH1A1 (0.72) | SMN1; SMN2MAPK1ALDH1A1TSHRRAB9A | |
| SCHEMBL1554443 | 0.89 | ALDH1A1 (0.72) | SMN1; SMN2MAPK1ALDH1A1TSHRRAB9A | |
| SCHEMBL18883201 | 0.89 | ALDH1A1 (0.72) | SMN1; SMN2MAPK1ALDH1A1TSHRRAB9A | |
| SCHEMBL1554157 | 0.89 | ALDH1A1 (0.72) | SMN1; SMN2MAPK1ALDH1A1TSHRRAB9A | |
| SCHEMBL8176787 | 0.88 | ALDH1A1 (0.71) | SMN1; SMN2MAPK1ALDH1A1TSHRRAB9A | |
| SCHEMBL10886640 | 0.85 | ALDH1A1 (0.81) | SMN1; SMN2MAPK1ALDH1A1TSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145885-A | Morpholine compound, binders | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| US-4582862-A | QUICK-SETTING PRINTING INKS BASED ON ACRYLATED RESINS | CIBA-GEIGY CORPORATION (US) | 1986-04-15 | — | — | US | disclosed |