Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.48 |
| ▸ | SORD | Q00796 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 7/20 | 0.47 |
| ▸ | HTR7 | P34969 | 4/20 | 0.47 |
| ▸ | DRD2 | P14416 | 4/20 | 0.45 |
| ▸ | HTR2A | P28223 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681618 | 0.85 | HTR2A (0.48) | DPP4DPP8DPP7HTR1AHTR7 | |
| SCHEMBL14046594 | 0.79 | SORD (0.54) | SORDHTR1AHTR7DRD2HTR2A | |
| SCHEMBL5095814 | 0.79 | DPP4 (0.49) | DPP4DPP8DPP7SORDHTR1A | |
| SCHEMBL13991484 | 0.77 | HRH3 (0.49) | DPP4DPP8DPP7SORDHTR1A | |
| SCHEMBL9377818 | 0.77 | HPGD (0.55) | SORDHTR1AHTR7DRD2HTR2A | |
| SCHEMBL3556933 | 0.76 | KDM4E (0.52) | HTR1ADRD2ALDH1A1LMNAMAPK1 | |
| SCHEMBL458698 | 0.76 | HPGD (0.58) | SORDHTR1ADRD2HTR2AMAPK1 | |
| SCHEMBL23064319 | 0.75 | SORD (0.50) | SORDHTR1AHTR7DRD2HTR2A | |
| SCHEMBL30778007 | 0.75 | SORD (0.50) | SORDHTR1AHTR7DRD2HTR2A | |
| SCHEMBL9190222 | 0.75 | HTR1A (0.50) | SORDHTR1AHTR7DRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173490-A | Antipsychotic drugs having no side effects; anxiolytic agents; analgesics; tranquilizers; sedatives; antidepressants | ADIR ET COMPAGNIE (FR) | 1992-12-22 | — | — | US | disclosed |
| EP-0494817-A1 | Benzisoxazole and benzisothiazole derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-07-15 | — | — | EP | disclosed |