Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 8/20 | 0.48 |
| ▸ | DRD2 | P14416 | 8/20 | 0.48 |
| ▸ | HTR1A | P08908 | 4/20 | 0.48 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9680137 | 0.85 | DPP4 (0.48) | HTR2ADRD2HTR1AHTR7ALDH1A1 | |
| SCHEMBL9377068 | 0.80 | ACHE (0.60) | HTR2ADRD2HTR1AHTR2CACHE | |
| SCHEMBL9187663 | 0.78 | HTR2A (0.53) | HTR2ADRD2HTR1AHTR7HTR2C | |
| Hydrochloric Acid SCHEMBL9722317 | 0.77 | HTR2A (0.52) | HTR2ADRD2HTR1AHTR7HTR2C | |
| SCHEMBL531012 | 0.76 | ACHE (0.52) | HTR2ADRD2HTR1AHTR7ALDH1A1 | |
| Hydrochloric Acid SCHEMBL14128737 | 0.75 | ACHE (0.51) | HTR2ADRD2HTR1AHTR7ALDH1A1 | |
| SCHEMBL2540345 | 0.75 | HTR2A (0.45) | HTR2ADRD2HTR1AHTR7KCNH2 | |
| SCHEMBL9722234 | 0.74 | HTR2A (0.60) | HTR2ADRD2HTR1AHTR7HTR2C | |
| SCHEMBL9722237 | 0.74 | HTR2A (0.60) | HTR2ADRD2HTR1AHTR7HTR2C | |
| SCHEMBL6218345 | 0.74 | DRD2 (0.47) | HTR2ADRD2HTR1AHTR7HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173490-A | Antipsychotic drugs having no side effects; anxiolytic agents; analgesics; tranquilizers; sedatives; antidepressants | ADIR ET COMPAGNIE (FR) | 1992-12-22 | — | — | US | claimed |
| EP-0494817-A1 | Benzisoxazole and benzisothiazole derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-07-15 | — | — | EP | claimed |
| US-5173490-A | Antipsychotic drugs having no side effects; anxiolytic agents; analgesics; tranquilizers; sedatives; antidepressants | ADIR ET COMPAGNIE (FR) | 1992-12-22 | — | — | US | disclosed |
| EP-0494817-A1 | Benzisoxazole and benzisothiazole derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-07-15 | — | — | EP | disclosed |