Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIMP3 | P35625 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | CASP6 | P55212 | 4/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9813346 | 0.82 | TIMP3 (0.51) | TIMP3LMNARAPGEF4ALDH1A1HSD17B10 | |
| SCHEMBL8981247 | 0.79 | TIMP3 (0.51) | TIMP3LMNARAPGEF4ALDH1A1HSD17B10 | |
| SCHEMBL9680143 | 0.78 | NT5E (0.53) | LMNAALDH1A1CYP2C19TDP1KDM4E | |
| SCHEMBL9680173 | 0.77 | ALDH1A1 (0.56) | LMNAALDH1A1HSD17B10KDM4EPOLB | |
| SCHEMBL9637465 | 0.77 | TIMP3 (0.44) | TIMP3LMNAALDH1A1HSD17B10KDM4E | |
| SCHEMBL9680216 | 0.76 | ALDH1A1 (0.51) | LMNAALDH1A1CASP6TDP1POLB | |
| SCHEMBL9329057 | 0.75 | TIMP3 (0.48) | TIMP3LMNARAPGEF4ALDH1A1HSD17B10 | |
| SCHEMBL10699443 | 0.74 | TIMP3 (0.47) | TIMP3LMNARAPGEF4ALDH1A1HSD17B10 | |
| SCHEMBL30084548 | 0.73 | ALDH1A1 (0.48) | TIMP3LMNAALDH1A1HSD17B10CASP6 | |
| SCHEMBL5409149 | 0.73 | ALDH1A1 (0.48) | TIMP3LMNAALDH1A1HSD17B10CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128455-A | WATER-SOLUBLE FIBER-REACTIVE DYES, CONTAINING AN AMINO-SUBSTITUTED 5-TRIAZINE RING WITH A FIBER-REACTIVE GROUP OF THE VINYLSULFONE SERIES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-07-07 | — | — | US | disclosed |
| EP-0374911-A1 | Water-soluble, fibre-reactive dyes, methods for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-06-27 | — | — | EP | disclosed |
| US-4912244-A | Vinylsulfonylalkylamino-alkylamines as intermediates for the preparation of fiber-reactive dyes | CIBA-GEIGY CORPORATION (US) | 1990-03-27 | — | — | US | disclosed |
| US-4782140-A | Triazinyl reactive dyes containing additional fiber reactive groups bound through the sulfonylalkylaminoalkylamino bridge | CIBA-GIEGY CORPORATION (US) | 1988-11-01 | — | — | US | disclosed |
| EP-0144766-B1 | REACTIVE DYES, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1988-10-05 | — | — | EP | disclosed |
| US-4754023-A | Reactive dyestuffs comprising a triazine moiety and a vinylsulfonyl moiety both being linked by a substituted alkylene bridge member | CIBA-GEIGY CORPORATION (US) | 1988-06-28 | — | — | US | disclosed |
| EP-0159292-B1 | REACTIVE DYES, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1988-01-07 | — | — | EP | disclosed |
| EP-0159292-A2 | Reactive dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1985-10-23 | — | — | EP | disclosed |
| EP-0144766-A2 | Reactive dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1985-06-19 | — | — | EP | disclosed |