SCHEMBL9680188

SCHEMBL9680188

C=CCn1cnc2cc(S(C)(=O)=O)ccc21

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.45
GHSR Q92847 1/20 0.42
KMT2A Q03164 1/20 0.42
NR1I2 O75469 11/20 0.40
HPGD P15428 1/20 0.36
C1S P09871 1/20 0.36
MAPT P10636 1/20 0.36
HSD17B10 Q99714 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
ADORA2B P29275 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1539109 0.86 CA9 (0.44) ALDH1A1KMT2ANR1I2C1SMAPT
SCHEMBL9678684 0.85 ALDH1A1 (0.43) ALDH1A1KMT2ANR1I2HPGD
SCHEMBL8874396 0.82 ALDH1A1 (0.59) ALDH1A1GHSRKMT2ANR1I2HPGD
SCHEMBL19848314 0.78 ALDH1A1 (0.47) ALDH1A1KMT2AHPGDMAPTHSD17B10
SCHEMBL5085201 0.77 NR1I2 (0.61) GHSRKMT2ANR1I2C1S
SCHEMBL9680193 0.76 FGFR1 (0.53) ALDH1A1KMT2AHPGDMAPTHDAC1
SCHEMBL13508799 0.76 KCNH2 (0.59) GHSRNR1I2
SCHEMBL1539112 0.75 PKM (0.60) ALDH1A1KMT2ANR1I2HPGDMAPT
SCHEMBL10893089 0.75 NPC1 (0.46) ALDH1A1KMT2ANR1I2HPGDMAPT
SCHEMBL10891799 0.75 MAPT (0.41) ALDH1A1KMT2AHPGDMAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5166046-A Light sensitive element with sensitizers KONICA CORPORATION (JP) 1992-11-24 US disclosed
EP-0439356-A1 Spectrally sensitized silver halide photographic material KONICA CORPORATION (JP) 1991-07-31 EP disclosed
US-4152163-A Silver halide photographic emulsion containing cyanine and hemicyanine sensitizing dyes FUJI PHOTO FILM CO., LTD. (JP) 1979-05-01 US disclosed
US-4147553-A CYANINE DYES FUJI PHOTO FILM CO., LTD. (JP) 1979-04-03 US disclosed