SCHEMBL30767397

SCHEMBL30767397

N[C@@H](Cc1c[nH]c2ccccc12)C(=O)Nc1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.71
KMT2A Q03164 3/20 0.71
MAPT P10636 3/20 0.71
KDM4E B2RXH2 2/20 0.71
LMNA P02545 1/20 0.71
MPO P05164 1/20 0.71
TSHR P16473 1/20 0.71
BLM P54132 1/20 0.71
PMP22 Q01453 1/20 0.71
HIF1A Q16665 1/20 0.71
RUVBL1 Q9Y265 4/20 0.68
AKT1 P31749 2/20 0.61
CDC7 O00311 1/20 0.61
CHUK O15111 1/20 0.61
MAPK13 O15264 1/20 0.61
DAPK3 O43293 1/20 0.61
DYRK3 O43781 1/20 0.61
ROCK2 O75116 1/20 0.61
RPS6KA5 O75582 1/20 0.61
PRKCG P05129 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9609465 1.00 MEN1 (0.71) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL9610738 1.00 MEN1 (0.71) MEN1KMT2AMAPTKDM4ELMNA
Hydrochloric Acid SCHEMBL19747056 0.99 MEN1 (0.69) MEN1KMT2AMAPTKDM4ELMNA
Hydrochloric Acid SCHEMBL21082966 0.99 MEN1 (0.69) MEN1KMT2AMAPTKDM4ELMNA
Hydrochloric Acid SCHEMBL19748758 0.95 RUVBL1 (0.73) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL11860142 0.92 RUVBL1 (0.65) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL28072305 0.92 RUVBL1 (0.65) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL8252240 0.91 RUVBL1 (0.70) MEN1KMT2AMAPTKDM4ELMNA
Hydrochloric Acid SCHEMBL19748580 0.91 RUVBL1 (0.63) MEN1KMT2AMAPTKDM4ELMNA
Hydrochloric Acid SCHEMBL19748954 0.91 RUVBL1 (0.63) MEN1KMT2AMAPTKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117603084-A Peptidase neurolysin enhancer and preparation method and application thereof 江苏瑞思坦生物科技有限公司 2024-02-27 CN claimed
CN-117603084-A Peptidase neurolysin enhancer and preparation method and application thereof 江苏瑞思坦生物科技有限公司 2024-02-27 CN disclosed