Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6989418 | 0.95 | MAPT (0.54) | KMT2AALDH1A1TDP1MAPK1MAPT | |
| SCHEMBL1205584 | 0.90 | KMT2A (0.60) | KMT2AALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL9695872 | 0.88 | KMT2A (0.57) | KMT2AALDH1A1MEN1HTTAGTR1 | |
| SCHEMBL1108437 | 0.83 | KMT2A (0.60) | KMT2AALDH1A1MAPTMEN1HTT | |
| SCHEMBL27869674 | 0.83 | ALDH1A1 (0.56) | KMT2AALDH1A1TDP1MAPK1MAPT | |
| SCHEMBL29179991 | 0.82 | KMT2A (0.52) | KMT2AALDH1A1MAPK1MAPTKDM4E | |
| SCHEMBL13332170 | 0.82 | MAPT (0.57) | KMT2AALDH1A1TDP1MAPK1MAPT | |
| SCHEMBL6696570 | 0.81 | CHRNB2 (0.54) | KMT2AALDH1A1TDP1MAPK1MAPT | |
| SCHEMBL765019 | 0.81 | PPARA (0.56) | KMT2ATDP1PPARGPPARACYP4F2 | |
| SCHEMBL12329630 | 0.81 | PPARA (0.56) | KMT2ATDP1PPARGPPARACYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5087721-A | Tumor-specific; for diagnosis and therapy | THE UNIVERSITY OF MICHIGAN (US) | 1992-02-11 | — | — | US | disclosed |
| US-4965391-A | Tumor specific | THE UNIVERSITY OF MICHIGAN (US) | 1990-10-23 | — | — | US | disclosed |