Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.37 |
| ▸ | FAP | Q12884 | 1/20 | 0.37 |
| ▸ | PRCP | P42785 | 2/20 | 0.36 |
| ▸ | ENO1 | P06733 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | TLR2 | O60603 | 2/20 | 0.34 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SCN4A | P35499 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL10553735 | 0.92 | HTR2C (0.34) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL2010421 | 0.87 | NOS2 (0.42) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL11247989 | 0.82 | ALDH1A1 (0.38) | LMNA | |
| SCHEMBL11247988 | 0.82 | ALDH1A1 (0.38) | LMNA | |
| SCHEMBL26116063 | 0.80 | PRCP (0.40) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL8815499 | 0.79 | DPP4 (0.38) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL10015337 | 0.79 | DPP4 (0.36) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL28238896 | 0.78 | SLC18A2 (0.34) | LMNACHRM2CHRM1 | |
| SCHEMBL133135 | 0.76 | PRCP (0.45) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL3330660 | 0.76 | PRCP (0.45) | DPP4DPP7DPP8DPP9FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272063-B1 | MITOMYCIN DERIVATIVES | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1992-04-08 | — | — | EP | disclosed |
| EP-0138403-B1 | PROCESS FOR PREPARING PHOSPHINIC ACID INTERMEDIATES | E.R. Squibb & Sons, Inc. (US) | 1989-03-15 | — | — | EP | disclosed |
| US-4602092-A | Method for making phosphinic acid intermediates | E. R. SQUIBB & SONS, INC. (US) | 1986-07-22 | — | — | US | disclosed |
| EP-0138403-A2 | Process for preparing phosphinic acid intermediates | E.R. Squibb & Sons, Inc. (US) | 1985-04-24 | — | — | EP | disclosed |