Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | TSHR | P16473 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL381975 | 0.83 | TSHR (0.52) | ALDH1A1TSHRSMN1; SMN2MAPK1HTT | |
| SCHEMBL1696905 | 0.81 | ALDH1A1 (0.56) | ALDH1A1TSHRSMN1; SMN2MAPK1HTT | |
| SCHEMBL29235961 | 0.79 | ALDH1A1 (0.53) | ALDH1A1TSHRSMN1; SMN2MAPK1HTT | |
| SCHEMBL5138794 | 0.79 | SLC6A3 (0.56) | ALDH1A1TSHRSMN1; SMN2MAPK1 | |
| SCHEMBL30484626 | 0.75 | ALDH1A1 (0.52) | ALDH1A1TSHRSMN1; SMN2MAPK1HTT | |
| SCHEMBL6201068 | 0.75 | ALDH1A1 (0.69) | ALDH1A1TSHRSMN1; SMN2MAPK1HTT | |
| SCHEMBL566913 | 0.75 | ALDH1A1 (0.52) | ALDH1A1TSHRSMN1; SMN2MAPK1HTT | |
| SCHEMBL14046498 | 0.73 | HRH3 (0.47) | ALDH1A1TSHRSMN1; SMN2MAPK1CYP3A4 | |
| SCHEMBL1980889 | 0.71 | ALDH1A1 (0.46) | ALDH1A1TSHRSMN1; SMN2MAPK1HTT | |
| SCHEMBL29236892 | 0.71 | ALDH1A1 (0.50) | ALDH1A1TSHRSMN1; SMN2MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145885-A | Morpholine compound, binders | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |