SCHEMBL6201068

SCHEMBL6201068

CSc1ccc(C(=O)C(C)CN2CCOCC2)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.69
LMNA P02545 7/20 0.69
CHRM2 P08172 2/20 0.53
ADRA2B P18089 2/20 0.53
DRD3 P35462 2/20 0.53
SIGMAR1 Q99720 2/20 0.53
HRH3 Q9Y5N1 2/20 0.53
SMN1; SMN2 Q16637 7/20 0.52
MAPK1 P28482 2/20 0.52
TSHR P16473 1/20 0.52
CYP2D6 P10635 1/20 0.51
ADRA2C P18825 1/20 0.51
CHRM3 P20309 1/20 0.51
OPRD1 P41143 1/20 0.51
KCNH2 Q12809 1/20 0.51
MAPT P10636 5/20 0.48
TP53 P04637 3/20 0.48
MITF O75030 2/20 0.48
HTT P42858 2/20 0.48
ATM Q13315 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11458967 0.87 LMNA (0.66) ALDH1A1LMNACHRM2ADRA2BDRD3
SCHEMBL11475420 0.86 CHRM2 (0.72) ALDH1A1LMNACHRM2ADRA2BDRD3
SCHEMBL10850475 0.85 ALDH1A1 (0.74) ALDH1A1LMNACHRM2ADRA2BDRD3
SCHEMBL11946057 0.83 ALDH1A1 (0.72) ALDH1A1LMNACHRM2ADRA2BDRD3
SCHEMBL14384871 0.83 ALDH1A1 (0.72) ALDH1A1LMNACHRM2ADRA2BDRD3
SCHEMBL10584214 0.83 ALDH1A1 (0.97) ALDH1A1LMNACHRM2ADRA2BDRD3
SCHEMBL9175526 0.82 CHRM2 (0.75) ALDH1A1LMNACHRM2ADRA2BDRD3
SCHEMBL11004686 0.81 ALDH1A1 (0.69) ALDH1A1LMNACHRM2ADRA2BDRD3
Hydrochloric Acid SCHEMBL11076147 0.80 ALDH1A1 (0.71) ALDH1A1LMNACHRM2ADRA2BDRD3
SCHEMBL13058950 0.80 ALDH1A1 (0.67) ALDH1A1LMNACHRM2ADRA2BDRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230185190-A1 PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE RESIN LAYER USING THE SAME AND COLOR FILTER SAMSUNG SDI CO., LTD. (KR) 2023-06-15 US disclosed
US-20230168463-A1 OPTICAL ELEMENT, OPTICAL DEVICE, AND IMAGE PICKUP APPARATUS CANON KABUSHIKI KAISHA (JP) 2023-06-01 US disclosed
EP-3638733-A1 COMPOSITION COMPRISING A FLUORINATED POLYMER AND A SILANE COMPOUND Arkema France (FR) 2020-04-22 EP disclosed
EP-3638732-A1 FLUORINATED POLYMER-BASED COMPOSITION HAVING IMPROVED ADHESION Arkema France (FR) 2020-04-22 EP disclosed
US-8227169-B2 Compound, acid generator, resist composition, and method of forming resist pattern TOKYO OHKA KOGYO CO., LTD. (JP) 2012-07-24 US disclosed
US-20100104973-A1 COMPOUND, ACID GENERATOR, RESIST COMPOSITION, AND METHOD OF FORMING RESIST PATTERN TOKYO OHKA KOGYO CO., LTD. 2010-04-29 US disclosed
EP-1549600-A1 KETONES AstraZeneca AB (SE) 2005-07-06 EP disclosed
WO-2004011410-A1 CHEMICAL COMPOUNDS ASTRAZENECA AB (SE) 2004-02-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100104973-A1 COMPOUND, ACID GENERATOR, RESIST COMPOSITION, AND METHOD OF FORMING RESIST PATTERN RER1, FRG1, C1R ALDH1A1 1068/4885LMNA 2943/4885CHRM2 101/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.