Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.54 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10558453 | 0.82 | HTT (0.62) | TAS1R3TAS1R1MAPK1HTTATM | |
| SCHEMBL255011 | 0.79 | HRH3 (0.53) | TAS1R3TAS1R1MAPK1HTTATM | |
| SCHEMBL10311684 | 0.79 | HTT (0.64) | TAS1R3TAS1R1MAPK1HTTATM | |
| SCHEMBL27263888 | 0.78 | RAB9A (0.58) | TAS1R3TAS1R1MAPK1HTTALDH1A1 | |
| SCHEMBL4575707 | 0.77 | MAPK1 (0.65) | TAS1R3TAS1R1MAPK1HTTALDH1A1 | |
| SCHEMBL29655342 | 0.77 | MAPK1 (0.65) | TAS1R3TAS1R1MAPK1HTTALDH1A1 | |
| SCHEMBL9680387 | 0.77 | HRH1 (0.54) | TAS1R3TAS1R1MAPK1HTTALDH1A1 | |
| SCHEMBL9680383 | 0.77 | LMNA (0.50) | TAS1R3TAS1R1MAPK1HTTATM | |
| SCHEMBL10448601 | 0.76 | HTT (0.56) | TAS1R3TAS1R1MAPK1HTTATM | |
| SCHEMBL48652 | 0.76 | HRH3 (0.61) | TAS1R3TAS1R1MAPK1HTTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272063-B1 | MITOMYCIN DERIVATIVES | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1992-04-08 | — | — | EP | disclosed |
| US-4863935-A | Mitomycin compounds having useful anti-tumor activity | KYOWA HAKKO KOGYO K.K. (JP) | 1989-09-05 | — | — | US | disclosed |