Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL255011 | 0.83 | HRH3 (0.53) | RAB9ANPC1MEN1KMT2AMAPK1 | |
| SCHEMBL2755853 | 0.77 | MAPK1 (0.60) | RAB9ANPC1MEN1KMT2AMAPK1 | |
| SCHEMBL30206599 | 0.77 | MAPK1 (0.60) | RAB9ANPC1MEN1KMT2AMAPK1 | |
| SCHEMBL9680393 | 0.77 | TAS1R3 (0.54) | RAB9ANPC1MEN1KMT2AMAPK1 | |
| SCHEMBL18381293 | 0.76 | KMT2A (0.55) | HRH1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL1694984 | 0.76 | RAB9A (0.62) | RAB9ANPC1MEN1KMT2AMAPK1 | |
| SCHEMBL27263888 | 0.76 | RAB9A (0.58) | RAB9ANPC1MEN1KMT2AMAPK1 | |
| SCHEMBL9680383 | 0.75 | LMNA (0.50) | RAB9ANPC1MEN1KMT2AMAPK1 | |
| SCHEMBL4575707 | 0.75 | MAPK1 (0.65) | RAB9ANPC1MEN1KMT2AMAPK1 | |
| SCHEMBL29655342 | 0.75 | MAPK1 (0.65) | RAB9ANPC1MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272063-B1 | MITOMYCIN DERIVATIVES | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1992-04-08 | — | — | EP | disclosed |
| US-4863935-A | Mitomycin compounds having useful anti-tumor activity | KYOWA HAKKO KOGYO K.K. (JP) | 1989-09-05 | — | — | US | disclosed |