Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL307830 | 0.84 | GSK3B (0.51) | MAPTLMNAGSK3BALDH1A1PKM | |
| SCHEMBL10458498 | 0.82 | ALDH1A1 (0.50) | MAPTALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL8898774 | 0.81 | PTPN1 (0.39) | MAPTLMNAGSK3BALDH1A1PKM | |
| SCHEMBL308691 | 0.80 | MAPT (0.52) | MAPTLMNAGSK3BALDH1A1PKM | |
| SCHEMBL8898946 | 0.80 | SMN1; SMN2 (0.43) | MAPTLMNAGSK3BALDH1A1KMT2A | |
| SCHEMBL9680487 | 0.77 | MAPT (0.46) | MAPTLMNAGSK3BALDH1A1PKM | |
| SCHEMBL10456874 | 0.77 | ALDH1A1 (0.44) | MAPTALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL26054728 | 0.76 | MAPT (0.57) | MAPTLMNAGSK3BALDH1A1PKM | |
| SCHEMBL9681281 | 0.76 | CA1 (0.47) | MAPTLMNAGSK3BALDH1A1PKM | |
| SCHEMBL10384876 | 0.76 | MLYCD (0.46) | MAPTLMNAALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145885-A | Morpholine compound, binders | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | claimed |
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | claimed |
| JP-3007772-A | — | — | None | — | — | JP | disclosed |
| US-5145885-A | Morpholine compound, binders | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| JP-H037772-A | ACTIVE ENERGY RAY-CURABLE COATING COMPOSITION | TOYO INK MFG CO LTD | 1991-01-14 | — | — | JP | disclosed |
| US-4960746-A | A-HYDROXY-OR A-AMINO-ACETOPHENONES AND A TITANOCENE COMPOUND SUBSTITUTED BY FLUORINE | CIBA-GEIGY CORPORATION (US) | 1990-10-02 | — | — | US | disclosed |