Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10384878 | 0.77 | POLB (0.42) | MAPTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL10384419 | 0.77 | CA1 (0.47) | MAPTLMNAGSK3BALDH1A1KMT2A | |
| SCHEMBL9680482 | 0.77 | MAPT (0.48) | MAPTLMNAGSK3BALDH1A1KMT2A | |
| SCHEMBL10384260 | 0.77 | CES1 (0.41) | LMNAKMT2ASMN1; SMN2HPGD | |
| SCHEMBL308819 | 0.77 | MAPT (0.55) | MAPTLMNAGSK3BALDH1A1KMT2A | |
| SCHEMBL9679848 | 0.75 | PPARA (0.42) | MAPTLMNAALDH1A1RAB9AATM | |
| SCHEMBL9766563 | 0.75 | TAS1R3 (0.42) | MAPTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL9766565 | 0.75 | ALDH1A1 (0.49) | MAPTLMNAALDH1A1NPC1TP53 | |
| SCHEMBL307565 | 0.75 | GSK3B (0.52) | MAPTLMNAGSK3BALDH1A1KMT2A | |
| SCHEMBL26054728 | 0.74 | MAPT (0.57) | MAPTLMNAGSK3BALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145885-A | Morpholine compound, binders | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| US-4960746-A | A-HYDROXY-OR A-AMINO-ACETOPHENONES AND A TITANOCENE COMPOUND SUBSTITUTED BY FLUORINE | CIBA-GEIGY CORPORATION (US) | 1990-10-02 | — | — | US | disclosed |