SCHEMBL968058

SCHEMBL968058

CCCCCN1CCSCC1

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GNAO1 P09471 7/20 0.52
GNAI3 P08754 6/20 0.52
GNAI1 P63096 6/20 0.52
TLR8 Q9NR97 1/20 0.42
TLR7 Q9NYK1 1/20 0.42
GUSB P08236 2/20 0.41
EBP Q15125 1/20 0.41
SIGMAR1 Q99720 1/20 0.41
S1PR1 P21453 1/20 0.41
S1PR3 Q99500 1/20 0.41
S1PR5 Q9H228 1/20 0.41
KDM4E B2RXH2 1/20 0.41
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15921159 0.98 GNAO1 (0.55) GNAO1GNAI3GNAI1GUSBEBP
SCHEMBL8429693 0.98 GNAO1 (0.55) GNAO1GNAI3GNAI1GUSBEBP
SCHEMBL10354337 0.98 GNAO1 (0.55) GNAO1GNAI3GNAI1GUSBEBP
SCHEMBL22222479 0.98 GNAO1 (0.55) GNAO1GNAI3GNAI1GUSBEBP
SCHEMBL10584652 0.98 GNAO1 (0.55) GNAO1GNAI3GNAI1GUSBEBP
SCHEMBL8431187 0.98 GNAO1 (0.55) GNAO1GNAI3GNAI1GUSBEBP
SCHEMBL17526500 0.98 GNAO1 (0.55) GNAO1GNAI3GNAI1GUSBEBP
SCHEMBL8283698 0.93 GNAI3 (0.43) GNAO1GNAI3GNAI1TLR8TLR7
SCHEMBL1920038 0.86 GNAI3 (0.44) GNAO1GNAI3GNAI1GUSBEBP
SCHEMBL17526515 0.85 GNAI3 (0.41) GNAO1GNAI3GNAI1GUSBS1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3794650-B1 ORGANIC SEMICONDUCTORS RAYNERGY TEK INC (TW) 2024-03-13 EP disclosed
US-20230374199-A1 ORGANIC SEMICONDUCTORS HOU JIANHUI (CN) 2023-11-23 US disclosed
US-11603431-B2 Organic semiconductors Raynergy Tek Incorporation (TW) 2023-03-14 US disclosed
EP-3411374-B9 [1,5]NAPHTHYRIDINE COMPOUNDS AND POLYMERS AS SEMICONDUCTORS RAYNERGY TEK INC (TW) 2023-01-11 EP disclosed
EP-4008708-A1 FULLERENE DERIVATIVES FOR ORGANIC SEMICONDUCTORS Nano-C, Inc. (US) 2022-06-08 EP disclosed
US-20220173321-A1 ORGANIC SEMICONDUCTORS RAYNERGY TEK INC (TW) 2022-06-02 US disclosed
EP-3430016-B1 ORGANIC SEMICONDUCTORS RAYNERGY TEK INC (TW) 2022-01-05 EP disclosed
EP-3157895-B1 FULLERENE DERIVATIVES FOR ORGANIC SEMICONDUCTORS NANO C INC (US) 2021-12-29 EP disclosed
EP-3070756-B9 SEMICONDUCTOR MIXTURES COMPRISING NANOPARTICLES RAYNERGY TEK INC (TW) 2021-11-03 EP disclosed
US-11130837-B2 Organic semiconductors Raynergy Tek Incorporation (TW) 2021-09-28 US disclosed
WO-2005060949-A2 SELECTIVE NOREPINEPHRINE REUPTAKE INHIBITORS FOR THE TREATMENT OF HOT FLASHES, IMPULSE CONTROL DISORDERS AND PERSONALITY CHANGE DUE TO A GENERAL MEDICAL CONDITION ELI LILLY AND COMPANY (US) 2005-07-07 WO disclosed
EP-1546123-A1 BENZYL MORPHOLINE DERIVATIVES ELI LILLY AND COMPANY (US) 2005-06-29 EP disclosed
WO-2005053663-A2 NOREPINEPHRINE REUPTAKE INHIBITORS USEFUL FOR TREATMENT OF COGNITIVE FAILURE ELI LILLY AND COMPANY (US) 2005-06-16 WO disclosed
EP-1534291-A2 2-(PHENOXYMETHYL)- AND 2-(PHENYLTHIOMETHYL)- MORPHOLINE DERIVATIVES FOR USE AS SELECTIVE NOREPINEPHRINE REUPTAKE INHIBITORS ELI LILLY AND COMPANY (US) 2005-06-01 EP disclosed
WO-2005020976-A2 TREATMENT OF PERVASIVE DEVELOPMENTAL DISORDERS WITH NOREPINEPHRINE REUPTAKE INHIBITORS ELI LILLY AND COMPANY (US) 2005-03-10 WO disclosed
WO-2005020975-A2 TREATMENT OF LEARNING DISABILITIES AND MOTOR SKILLS DISORDER WITH NOREPINEPHRINE REUPTAKE INHIBITORS ELI LILLY AND COMPANY (US) 2005-03-10 WO disclosed
WO-2005021095-A2 TREATMENT OF STUTTERING AND OTHER COMMUNICATION DISORDERS WITH NOREPINEPHRINE REUPTAKE INHIBITORS ELI LILLY AND COMPANY (US) 2005-03-10 WO disclosed
WO-2004103356-A2 TREATMENT OF EMOTIONAL DYSREGULATION ELI LILLY AND COMPANY (US) 2004-12-02 WO disclosed
WO-2004017977-A2 2- (PHENOXYMETHYL)- AND 2- (PHENYLTHIOMETHYL)-MORPHOLINE DERIVATIVES FOR USE AS SELECTIVE NOREPINEPHRINE REUPTAKE INHIBITORS ELI LILLY AND COMPANY (US) 2004-03-04 WO disclosed
WO-2004018440-A1 BENZYL MORPHOLINE DERIVATIVES ELI LILLY AND COMPANY (US) 2004-03-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11603431-B2 Organic semiconductors OCIAD2, OCIAD1, PPOX GNAO1 1294/4885GNAI3 2462/4885GNAI1 2008/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.