Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 3/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.55 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.45 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.45 |
| ▸ | FLT4 | P35916 | 1/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.45 |
| ▸ | RET | P07949 | 9/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5150675 | 0.78 | ADORA1 (0.56) | ADORA1ADORA2A | |
| SCHEMBL14697371 | 0.75 | ADORA1 (0.53) | ADORA1ADORA2A | |
| SCHEMBL10707090 | 0.75 | NPSR1 (0.43) | ADORA1ADORA2A | |
| SCHEMBL10611187 | 0.72 | ADORA1 (0.61) | ADORA1ADORA2A | |
| SCHEMBL9649847 | 0.72 | ADORA2A (0.57) | ADORA1ADORA2ADYRK1A | |
| SCHEMBL9350241 | 0.71 | ADORA2A (0.54) | ADORA1ADORA2AMAPK10 | |
| SCHEMBL4468508 | 0.70 | ALDH1A1 (0.46) | ADORA1 | |
| SCHEMBL8309258 | 0.68 | ADORA1 (0.48) | ADORA1ADORA2AMAPK8MAPK9FLT4 | |
| SCHEMBL18513465 | 0.68 | KDR (0.66) | ADORA1ADORA2AMAPK8MAPK9MAPK10 | |
| SCHEMBL30280660 | 0.68 | LRRK2 (0.48) | ADORA1ADORA2AMAPK8MAPK9FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132412-A | Textile fibers | BASF AKTIENGESELLSCHAFT (DE) | 1992-07-21 | — | — | US | disclosed |