Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PTPRZ1 | P23471 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6001741 | 0.80 | ALDH1A1 (0.56) | KDM4EALDH1A1TDP1MAPTRAB9A | |
| SCHEMBL9611202 | 0.80 | FFAR1 (0.59) | KDM4EALDH1A1TDP1FFAR1MAPT | |
| SCHEMBL4970529 | 0.77 | MAPT (0.67) | FFAR1MAPTADRB2RAB9AL3MBTL1 | |
| SCHEMBL9611201 | 0.77 | MAPT (0.67) | FFAR1MAPTADRB2RAB9AL3MBTL1 | |
| SCHEMBL4968126 | 0.76 | CYP3A4 (0.58) | ALDH1A1TDP1FFAR1MAPTADRB2 | |
| SCHEMBL9195087 | 0.75 | FFAR1 (0.51) | FFAR1MAPTADRB2RAB9AL3MBTL1 | |
| SCHEMBL29574292 | 0.75 | ALDH1A1 (0.56) | KDM4EALDH1A1TDP1MAPTTSHR | |
| SCHEMBL656796 | 0.75 | ALDH1A1 (0.56) | KDM4EALDH1A1TDP1MAPTTSHR | |
| SCHEMBL29462452 | 0.74 | MAPT (0.62) | KDM4EALDH1A1TDP1FFAR1MAPT | |
| SCHEMBL2811255 | 0.74 | MAPT (0.62) | KDM4EALDH1A1TDP1FFAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0493650-A1 | Fluorinated acetylene-containing aromatic amines and diamines | National Starch and Chemical Investment Holding Corporation (US) | 1992-07-08 | — | — | EP | disclosed |
| US-5107026-A | Fluorinated acetylene-containing aromatic amines and diamines | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1992-04-21 | — | — | US | disclosed |