Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 3/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24977286 | 0.86 | EPHX2 (0.41) | NOTUMRAB9ANPC1LMNAKDM4E | |
| SCHEMBL29541410 | 0.80 | NOTUM (0.41) | NOTUMRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL29541827 | 0.77 | BCAT1 (0.46) | NOTUMRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL7843687 | 0.76 | NOTUM (0.50) | NOTUMRAB9ANPC1LMNAKDM4E | |
| SCHEMBL29541546 | 0.76 | CYP1A2 (0.47) | NOTUMRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL6817772 | 0.76 | CYP1A2 (0.47) | NOTUMRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL14125002 | 0.74 | NOTUM (0.56) | NOTUMRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL4053984 | 0.74 | EPHX2 (0.49) | NOTUMRAB9AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL24978464 | 0.72 | SYK (0.55) | RAB9ANPC1CYP1A2CYP19A1CYP2C9 | |
| SCHEMBL3689041 | 0.68 | NPC1 (0.35) | RAB9ANPC1LMNAPDE4BCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0486782-A1 | Improved process for the synthesis of alpha-((dialkylamino)substituted-methylene)-beta-oxo-(substituted) propanenitriles | AMERICAN CYANAMID COMPANY (US) | 1992-05-27 | — | — | EP | claimed |
| US-5103015-A | 5-(substituted)isoxazole compounds | AMERICAN CYANAMID COMPANY (US) | 1992-04-07 | — | — | US | claimed |
| US-11306078-B2 | Piperidine CXCR7 receptor modulators | IDORSIA PHARMACEUTICALS LTD. (CH) | 2022-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11306078-B2 | Piperidine CXCR7 receptor modulators | CXCR1, CXCR5, ACKR3 | NOTUM 4727/4885RAB9A 1065/4885NPC1 1403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.