Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11263701 | 0.94 | ALDH1A1 (0.47) | ALDH1A1MAPK1PARP10MEN1KMT2A | |
| SCHEMBL9680403 | 0.86 | HPGD (0.52) | ALDH1A1MAPK1MEN1KMT2ALMNA | |
| SCHEMBL1553060 | 0.86 | ALDH1A1 (0.60) | ALDH1A1MAPK1PARP10SRD5A2MEN1 | |
| SCHEMBL3007482 | 0.84 | HPGD (0.48) | ALDH1A1MAPK1MEN1KMT2ALMNA | |
| SCHEMBL9681617 | 0.83 | HPGD (0.57) | ALDH1A1MEN1KMT2ALMNAGAA | |
| SCHEMBL9680438 | 0.83 | ALDH1A1 (0.54) | ALDH1A1MAPK1SRD5A2MEN1KMT2A | |
| SCHEMBL10943797 | 0.83 | CES2 (0.48) | ALDH1A1MAPK1KMT2ALMNANPC1 | |
| SCHEMBL9681651 | 0.81 | HPGD (0.58) | ALDH1A1MAPK1MEN1KMT2ALMNA | |
| SCHEMBL10944199 | 0.81 | ALDH1A1 (0.56) | ALDH1A1MAPK1SRD5A2MEN1KMT2A | |
| SCHEMBL9680468 | 0.79 | ALDH1A1 (0.52) | ALDH1A1MAPK1LMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145885-A | Morpholine compound, binders | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| US-4960746-A | A-HYDROXY-OR A-AMINO-ACETOPHENONES AND A TITANOCENE COMPOUND SUBSTITUTED BY FLUORINE | CIBA-GEIGY CORPORATION (US) | 1990-10-02 | — | — | US | disclosed |