Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MLYCD | O95822 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681301 | 0.88 | MLYCD (0.45) | ALDH1A1HPGDRAB9AHTTMLYCD | |
| SCHEMBL9681281 | 0.83 | CA1 (0.47) | ALDH1A1RAB9AMLYCDMAPTNPC1 | |
| SCHEMBL10384876 | 0.83 | MLYCD (0.46) | ALDH1A1HPGDRAB9AMLYCDMAPT | |
| SCHEMBL10384259 | 0.83 | CES1 (0.45) | HPGDMLYCDMAPTTSHRHSD17B10 | |
| SCHEMBL4421870 | 0.81 | MLYCD (0.44) | ALDH1A1HPGDRAB9AHTTMLYCD | |
| SCHEMBL725631 | 0.81 | MLYCD (0.44) | ALDH1A1HTTMLYCDMAPTKDM4E | |
| SCHEMBL9679833 | 0.81 | PPARA (0.45) | ALDH1A1HPGDRAB9AMLYCDMAPT | |
| SCHEMBL4418642 | 0.79 | MLYCD (0.43) | ALDH1A1HPGDRAB9AHTTMLYCD | |
| SCHEMBL9766579 | 0.78 | MLYCD (0.42) | ALDH1A1HPGDRAB9AHTTMLYCD | |
| SCHEMBL9679941 | 0.77 | ALDH1A1 (0.46) | ALDH1A1HPGDRAB9AHTTMLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145885-A | Morpholine compound, binders | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| US-4960746-A | A-HYDROXY-OR A-AMINO-ACETOPHENONES AND A TITANOCENE COMPOUND SUBSTITUTED BY FLUORINE | CIBA-GEIGY CORPORATION (US) | 1990-10-02 | — | — | US | disclosed |