Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NAMPT | P43490 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 4/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | ESRRG | P62508 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681018 | 0.88 | ALDH1A1 (0.50) | MLYCDALDH1A1HTTRAB9AHPGD | |
| SCHEMBL10384876 | 0.83 | MLYCD (0.46) | MLYCDALDH1A1RAB9AHPGDMAPT | |
| SCHEMBL9681281 | 0.83 | CA1 (0.47) | MLYCDALDH1A1RAB9AHDAC4HDAC1 | |
| SCHEMBL10384259 | 0.83 | CES1 (0.45) | MLYCDHPGDMAPTMEN1KMT2A | |
| SCHEMBL725631 | 0.81 | MLYCD (0.44) | MLYCDALDH1A1HTTHDAC4MAPT | |
| SCHEMBL9679833 | 0.81 | PPARA (0.45) | MLYCDALDH1A1RAB9AHPGDMAPT | |
| SCHEMBL4421870 | 0.81 | MLYCD (0.44) | MLYCDALDH1A1NAMPTHTTRAB9A | |
| SCHEMBL17502989 | 0.80 | HPGD (0.48) | MLYCDALDH1A1NAMPTHTTRAB9A | |
| SCHEMBL4418642 | 0.79 | MLYCD (0.43) | MLYCDALDH1A1NAMPTHTTRAB9A | |
| SCHEMBL9766579 | 0.78 | MLYCD (0.42) | MLYCDALDH1A1NAMPTHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145885-A | Morpholine compound, binders | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |