SCHEMBL9680722

SCHEMBL9680722

Cc1cccc(N)c1-c1ccc(O)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SENP1 Q9P0U3 1/20 0.48
CD44 P16070 1/20 0.46
USP7 Q93009 2/20 0.43
CYP3A4 P08684 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
ESR1 P03372 5/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
ESR2 Q92731 4/20 0.41
MAPK1 P28482 1/20 0.41
MAP2K4 P45985 1/20 0.41
MAPKAPK2 P49137 1/20 0.41
MAPK6 Q16659 1/20 0.41
MGAM O43451 1/20 0.41
GAA P10253 1/20 0.41
SI P14410 1/20 0.41
MGAM2 Q2M2H8 1/20 0.41
TSHR P16473 1/20 0.41
PIK3CA P42336 1/20 0.41
ALDH1A1 P00352 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28860865 0.87 ESR1 (0.48) SENP1USP7CYP3A4ESR1MEN1
SCHEMBL25011940 0.87 CD44 (0.54) CD44CYP3A4TDP1TSHRPIK3CA
SCHEMBL6288837 0.87 SENP1 (0.56) SENP1USP7ESR1MEN1KMT2A
SCHEMBL9681003 0.83 CD44 (0.50) CD44CYP3A4TDP1GAATSHR
SCHEMBL3789888 0.83 CD44 (0.50) CD44CYP3A4TDP1TSHRPIK3CA
SCHEMBL2936698 0.81 ALOX15 (0.46) SENP1ESR1MEN1KMT2AESR2
SCHEMBL3793739 0.80 CYP3A4 (0.54) CD44CYP3A4TDP1KMT2ATSHR
SCHEMBL27736524 0.80 HSD17B1 (0.50) CD44CYP3A4TDP1ESR1ESR2
SCHEMBL9681067 0.79 CD44 (0.46) CD44CYP3A4TDP1MGAMGAA
Hydrochloric Acid SCHEMBL2938598 0.79 ALOX15 (0.44) SENP1ESR1MEN1KMT2AESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107921293-A Kit for dyeing and/or bleaching keratin fibres comprising an alkaline agent, an oxidizing agent and an openable and closable airtight container 欧莱雅 2018-04-17 CN disclosed
CN-106890110-A Use the direct emulsion comprising oxidant and the hair treatment method of the composition containing alkaline agent 莱雅公司 2017-06-27 CN disclosed
US-5153226-A Administering as anticholesterol agents, for atherosclerosis WARNER-LAMBERT COMPANY (US) 1992-10-06 US disclosed