Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 4/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.52 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL56823 | 0.86 | HTT (0.58) | LMNAHTTPKMTSHRTDP1 | |
| SCHEMBL111537 | 0.86 | TSHR (0.73) | LMNAHTTPKMTSHRTDP1 | |
| SCHEMBL29390085 | 0.86 | TSHR (0.73) | LMNAHTTPKMTSHRTDP1 | |
| SCHEMBL6574005 | 0.86 | HTT (0.58) | LMNAHTTPKMTSHRTDP1 | |
| SCHEMBL27510433 | 0.84 | HTT (0.57) | LMNAHTTPKMTSHRTDP1 | |
| SCHEMBL2716434 | 0.84 | LMNA (0.70) | LMNAHTTPKMTDP1ALDH1A1 | |
| SCHEMBL6559600 | 0.84 | ALDH1A1 (0.67) | LMNAHTTTSHRTDP1ALDH1A1 | |
| SCHEMBL21280225 | 0.84 | HTT (0.62) | LMNAHTTPKMALDH1A1MAPT | |
| SCHEMBL3125877 | 0.83 | TSHR (0.55) | LMNAHTTTSHRTDP1ALDH1A1 | |
| SCHEMBL10139198 | 0.83 | MAPT (0.62) | LMNAHTTTSHRTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5167669-A | Hair dyes | L'OREAL (FR) | 1992-12-01 | — | — | US | disclosed |
| US-5096455-A | PROCESS FOR DYEING KERATINOUS FIBRES EMPLOYING AN INDOLE DYE AND AT LEAST ONE PARA-PHENYLENEDIAMINE CONTAINING A SECONDARY AMINO GROUP ABSENT AN OXIDANT OTHER THAN AIR | L'OREAL (FR) | 1992-03-17 | — | — | US | disclosed |