Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ECE1 | P42892 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10719844 | 0.80 | HDAC1 (0.47) | THRBHDAC1HDAC6LMNAHIF1A | |
| SCHEMBL7678624 | 0.77 | AGTR1 (0.46) | HDAC1HDAC6RAB9AROCK2EPHX2 | |
| SCHEMBL10593276 | 0.74 | ALDH1A1 (0.54) | THRBHDAC1HDAC6LMNAHIF1A | |
| SCHEMBL10645039 | 0.73 | HDAC1 (0.54) | THRBHDAC1HDAC6LMNAHIF1A | |
| SCHEMBL9681833 | 0.72 | ALDH1A1 (0.43) | LMNAHIF1ASMN1; SMN2CYP2C19MEN1 | |
| SCHEMBL3616505 | 0.72 | HDAC1 (0.56) | THRBHDAC1HDAC6LMNAHIF1A | |
| SCHEMBL8802116 | 0.69 | RAB9A (0.42) | LMNARAB9ANPC1TP53SMN1; SMN2 | |
| SCHEMBL10702217 | 0.68 | RAB9A (0.50) | HDAC1HDAC6LMNAHIF1ARAB9A | |
| SCHEMBL10525208 | 0.68 | HDAC1 (0.48) | THRBHDAC1HDAC6LMNAHIF1A | |
| SCHEMBL10525214 | 0.68 | HDAC1 (0.48) | THRBHDAC1HDAC6LMNAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5126362-A | Substituted pyrazoylacetamides | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1992-06-30 | — | — | US | disclosed |
| EP-0361362-A1 | Oxime derivative and fungicide for agricultural and horticultural use | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1990-04-04 | — | — | EP | disclosed |