Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.44 |
| ▸ | TUBB | P07437 | 2/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.44 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.44 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.44 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.44 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.44 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5537261 | 0.80 | PTGS2 (0.47) | PTGS2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL2759516 | 0.78 | PTGS2 (0.54) | PTGS2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1651683 | 0.77 | ACHE (0.52) | PTGS2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4587193 | 0.77 | PTGS2 (0.44) | PTGS2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL23011878 | 0.76 | MAPT (0.50) | PTGS2TUBB4ATUBBTUBA3CTUBA1B | |
| Hydrochloric Acid SCHEMBL27871982 | 0.76 | PTGS2 (0.52) | PTGS2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL14195838 | 0.76 | PTGS2 (0.47) | PTGS2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL12963092 | 0.74 | PTGS2 (0.50) | PTGS2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9823158 | 0.73 | PTGS2 (0.44) | PTGS2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9525237 | 0.73 | CYP3A4 (0.47) | PTGS2TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116954-A | Antitumor agents | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1992-05-26 | — | — | US | disclosed |