Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10727902 | 0.93 | LMNA (0.46) | MAPTLMNAL3MBTL1GAANPSR1 | |
| SCHEMBL10731867 | 0.88 | TSHR (0.50) | MAPTLMNAL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL9124986 | 0.86 | ALDH1A1 (0.52) | MAPTLMNAL3MBTL1ALDH1A1TSHR | |
| SCHEMBL28837381 | 0.86 | TSHR (0.53) | MAPTLMNAL3MBTL1GAANPSR1 | |
| SCHEMBL9680549 | 0.84 | CYP3A4 (0.49) | MAPTLMNAL3MBTL1GAANPSR1 | |
| SCHEMBL52126 | 0.84 | TSHR (0.46) | MAPTLMNAL3MBTL1GAANPSR1 | |
| SCHEMBL29447786 | 0.84 | TSHR (0.46) | MAPTLMNAL3MBTL1GAANPSR1 | |
| SCHEMBL10730528 | 0.83 | LMNA (0.54) | MAPTLMNAL3MBTL1GAAALDH1A1 | |
| SCHEMBL29206737 | 0.83 | LMNA (0.37) | MAPTLMNAL3MBTL1GAANPSR1 | |
| SCHEMBL28837409 | 0.82 | GABRP (0.47) | MAPTLMNAL3MBTL1GAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145885-A | Morpholine compound, binders | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| US-4681950-A | PHOTOSENSITIZERS | CIBA-GEIGY CORPORATION (US) | 1987-07-21 | — | — | US | disclosed |
| US-4585876-A | PHOTOSENSITIZERS | CIBA-GEIGY CORPORATION (US) | 1986-04-29 | — | — | US | disclosed |
| EP-0138754-A2 | Photocurable compositions | CIBA-GEIGY AG (CH) | 1985-04-24 | — | — | EP | disclosed |