Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5696701 | 0.85 | HTT (0.42) | KMT2ASIGMAR1CHRM2CHRM4CHRM5 | |
| SCHEMBL9330548 | 0.81 | KDM4E (0.40) | KMT2ACHRM2POLBSMN1; SMN2OPRK1 | |
| SCHEMBL9683488 | 0.80 | GRIN2B (0.40) | OPRM1OPRD1OPRK1OPRL1TDP1 | |
| SCHEMBL9152803 | 0.79 | MEN1 (0.47) | KMT2ACHRM2OPRK1LMNA | |
| SCHEMBL900832 | 0.78 | MEN1 (0.37) | KMT2ACA1CA2CA7CA9 | |
| SCHEMBL5144549 | 0.74 | CHRM2 (0.39) | KMT2ASIGMAR1CHRM2CHRM4CHRM5 | |
| SCHEMBL20957985 | 0.72 | ALDH1A1 (0.54) | POLBALDH1A1KDM4EHSD17B10TDP1 | |
| SCHEMBL9683216 | 0.71 | TSHR (0.35) | KMT2ACHRM1CA1CA2CA7 | |
| SCHEMBL7427848 | 0.70 | SMN1; SMN2 (0.39) | KMT2ASMN1; SMN2HTTALDH1A1KDM4E | |
| SCHEMBL10480053 | 0.69 | PTGS2 (0.42) | KMT2ACHRM2CHRM1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2060923-A | — | — | None | — | — | JP | disclosed |
| US-5089590-A | LIQUID CRYSTALLINE COMPOUNDS, THEIR PRODUCTION AND THEIR USE AS MODIFIERS FOR POLYCARBONATES, POLYESTER CARBONATES AND POLYESTERS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| US-5084549-A | Aromatic polyesters as thermoplastic molding materials | BAYER AKTIENGESELLSCHAFT (DE) | 1992-01-28 | — | — | US | disclosed |
| US-5043403-A | Polycarbonates containing mesogenic compounds as end groups, their preparation and their use | BAYER AKTIENGESELLSCHAFT (DE) | 1991-08-27 | — | — | US | disclosed |
| JP-H0260923-A | POLYCARBONATE CONTAINING MESOGENIC COMPOUNDS AS TERMINAL GROUP, AND ITS MANUFACTURE AND USE THEREOF | BAYER AG | 1990-03-01 | — | — | JP | disclosed |