Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | BACE1 | P56817 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.49 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9683222 | 0.90 | SMN1; SMN2 (0.64) | SMN1; SMN2BACE1MAPTHSD17B10ESR2 | |
| SCHEMBL7591657 | 0.88 | SMN1; SMN2 (0.75) | SMN1; SMN2BACE1MAPTHSD17B10GPR35 | |
| SCHEMBL11031817 | 0.87 | ABL1 (0.53) | SMN1; SMN2MAPTHSD17B10KDM4EALDH1A1 | |
| SCHEMBL2785635 | 0.86 | HSD17B10 (0.68) | HSD17B10ESR2ALDH1A1CYP1A2 | |
| SCHEMBL8458268 | 0.84 | NPC1 (0.56) | SMN1; SMN2BACE1MAPTHSD17B10ESR2 | |
| SCHEMBL20695878 | 0.84 | HSD17B10 (0.66) | HSD17B10ESR2ALDH1A1MEN1KMT2A | |
| SCHEMBL900834 | 0.84 | HSD17B10 (0.71) | HSD17B10ESR2ALDH1A1 | |
| SCHEMBL10993825 | 0.84 | SMN1; SMN2 (0.64) | SMN1; SMN2GPR35KDM4EALDH1A1RXFP1 | |
| SCHEMBL5696709 | 0.84 | SMN1; SMN2 (0.64) | SMN1; SMN2BACE1MAPTGPR35KDM4E | |
| SCHEMBL8458979 | 0.83 | NPC1 (0.55) | SMN1; SMN2BACE1MAPTHSD17B10ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2060923-A | — | — | None | — | — | JP | disclosed |
| US-5089590-A | LIQUID CRYSTALLINE COMPOUNDS, THEIR PRODUCTION AND THEIR USE AS MODIFIERS FOR POLYCARBONATES, POLYESTER CARBONATES AND POLYESTERS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| US-5084549-A | Aromatic polyesters as thermoplastic molding materials | BAYER AKTIENGESELLSCHAFT (DE) | 1992-01-28 | — | — | US | disclosed |
| US-5043403-A | Polycarbonates containing mesogenic compounds as end groups, their preparation and their use | BAYER AKTIENGESELLSCHAFT (DE) | 1991-08-27 | — | — | US | disclosed |
| JP-H0260923-A | POLYCARBONATE CONTAINING MESOGENIC COMPOUNDS AS TERMINAL GROUP, AND ITS MANUFACTURE AND USE THEREOF | BAYER AG | 1990-03-01 | — | — | JP | disclosed |