Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.49 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.49 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.49 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.49 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.49 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.49 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8566031 | 0.90 | SMN1; SMN2 (0.64) | SMN1; SMN2AKR1C3AKR1C2KDM4EALDH1A1 | |
| SCHEMBL7591657 | 0.88 | SMN1; SMN2 (0.75) | SMN1; SMN2AKR1C3AKR1C2KDM4EALDH1A1 | |
| SCHEMBL6498971 | 0.86 | HDAC7 (0.57) | SMN1; SMN2AKR1C3AKR1C2ALDH1A1GAA | |
| SCHEMBL9681370 | 0.84 | SMN1; SMN2 (0.64) | SMN1; SMN2KDM4EALDH1A1GAARXFP1 | |
| SCHEMBL10993825 | 0.84 | SMN1; SMN2 (0.64) | SMN1; SMN2AKR1C3AKR1C2KDM4EALDH1A1 | |
| SCHEMBL16527361 | 0.83 | SMN1; SMN2 (0.62) | SMN1; SMN2AKR1C3AKR1C2KDM4EALDH1A1 | |
| SCHEMBL9683573 | 0.81 | HSD17B10 (0.58) | SMN1; SMN2AKR1C2ALDH1A1GAAPRKAB2 | |
| SCHEMBL11154359 | 0.81 | ALDH1A1 (0.55) | SMN1; SMN2AKR1C3KDM4EALDH1A1GAA | |
| SCHEMBL3229733 | 0.81 | HDAC7 (0.70) | AKR1C3AKR1C2KDM4EALDH1A1GAA | |
| SCHEMBL30073152 | 0.81 | PRSS1 (0.48) | SMN1; SMN2ALDH1A1GAARXFP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1118644-B1 | Hot melt printing ink | SIEGWERK DRUCKFARBEN AG (DE) | 2006-06-14 | — | — | EP | disclosed |
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | DAISO CO., LTD. (JP) | 2005-02-17 | — | — | US | disclosed |
| US-20040157866-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
| EP-1118644-A2 | Hot melt printing ink | Siegwerk Druckfarben GmbH & Co. KG (DE) | 2001-07-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157866-A1 | Amide compounds | APOB, NR1H2, NR1H3 | SMN1; SMN2 1854/4885AKR1C3 367/4885AKR1C2 503/4885 |
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | APOB, APOL1, CTRB2 | SMN1; SMN2 1921/4885AKR1C3 412/4885AKR1C2 679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.