Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7591657 | 0.92 | SMN1; SMN2 (0.75) | SMN1; SMN2HSD17B10ALDH1A1HPGDCYP1A2 | |
| SCHEMBL9681370 | 0.90 | SMN1; SMN2 (0.64) | SMN1; SMN2HSD17B10NPC1RAB9AESR2 | |
| SCHEMBL9151080 | 0.87 | SMN1; SMN2 (0.64) | SMN1; SMN2ALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8566031 | 0.87 | SMN1; SMN2 (0.64) | SMN1; SMN2HSD17B10NPC1RAB9AALDH1A1 | |
| SCHEMBL6701301 | 0.87 | SMN1; SMN2 (0.63) | SMN1; SMN2ALDH1A1HPGDMAPK1CYP1A2 | |
| SCHEMBL1359389 | 0.86 | SMN1; SMN2 (0.62) | SMN1; SMN2HSD17B10NPC1RAB9AALDH1A1 | |
| SCHEMBL6778891 | 0.86 | SMN1; SMN2 (0.62) | SMN1; SMN2NPC1RAB9AALDH1A1CYP1A2 | |
| SCHEMBL8460808 | 0.84 | ALDH1A1 (0.57) | SMN1; SMN2HSD17B10NPC1RAB9AESR2 | |
| SCHEMBL8069413 | 0.83 | SMN1; SMN2 (0.59) | SMN1; SMN2HSD17B10NPC1RAB9AALDH1A1 | |
| SCHEMBL8458977 | 0.83 | NPC1 (0.59) | SMN1; SMN2HSD17B10NPC1RAB9AESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089590-A | LIQUID CRYSTALLINE COMPOUNDS, THEIR PRODUCTION AND THEIR USE AS MODIFIERS FOR POLYCARBONATES, POLYESTER CARBONATES AND POLYESTERS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| US-5084549-A | Aromatic polyesters as thermoplastic molding materials | BAYER AKTIENGESELLSCHAFT (DE) | 1992-01-28 | — | — | US | disclosed |
| EP-0347682-A2 | Polycarbonates with mesogenic compounds as end groups, their preparation and their use | BAYER AG (DE) | 1989-12-27 | — | — | EP | disclosed |