Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.43 |
| ▸ | EBP | Q15125 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9677487 | 0.92 | SMN1; SMN2 (0.43) | ABCB1EBPSIGMAR1HTR1ASLC6A4 | |
| SCHEMBL9678100 | 0.83 | KCNH2 (0.48) | ABCB1EBPSIGMAR1HTR1ASLC6A4 | |
| SCHEMBL9444367 | 0.83 | ABCB1 (0.61) | ABCB1EBPSIGMAR1HTR1ASLC6A4 | |
| SCHEMBL9447564 | 0.81 | ABCB1 (0.45) | ABCB1EBPSIGMAR1HTR1ASLC6A4 | |
| SCHEMBL9444495 | 0.80 | KCNH2 (0.58) | ABCB1KCNH2ALDH1A1HTTKMT2A | |
| Hydrochloric Acid SCHEMBL9444430 | 0.79 | KCNH2 (0.59) | ABCB1KCNH2ALDH1A1HTTKMT2A | |
| SCHEMBL9041547 | 0.78 | ABCB1 (0.43) | ABCB1EBPSIGMAR1HTR1ASLC6A4 | |
| SCHEMBL9676471 | 0.78 | ALDH1A1 (0.44) | HTR1AKCNH2ALDH1A1 | |
| SCHEMBL7028266 | 0.77 | HTR2A (0.48) | ABCB1EBPSIGMAR1HTR1ASLC6A4 | |
| SCHEMBL10645360 | 0.76 | KMT2A (0.54) | ABCB1EBPSIGMAR1TMEM97ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162347-A | Piperidine derivatives and therapeutic and preventive agents for arrhythmia containing same | EISAI CO., LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| US-5082850-A | PIPERIDINE DERIVATIVES AND THERAPEUTIC AND PREVENTIVE AGENTS FOR ARRHYTHMIA CONTAINING SAME | EISAI CO., LTD. (JP) | 1992-01-21 | — | — | US | disclosed |
| US-4977165-A | Piperidine derivative and therapeutic and preventive agents for arrhythmia containing same | EISAI CO., LTD. (JP) | 1990-12-11 | — | — | US | disclosed |