Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | EBP | Q15125 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681410 | 0.92 | ABCB1 (0.43) | ALDH1A1HTR1ASLC6A4EBPSIGMAR1 | |
| SCHEMBL7028266 | 0.76 | HTR2A (0.48) | HTR1ASLC6A4EBPSIGMAR1TMEM97 | |
| SCHEMBL10523855 | 0.75 | ALDH1A1 (0.42) | ALDH1A1HTR1ASLC6A4EBPSIGMAR1 | |
| SCHEMBL9678100 | 0.75 | KCNH2 (0.48) | ALDH1A1HTR1ASLC6A4EBPSIGMAR1 | |
| SCHEMBL9444367 | 0.75 | ABCB1 (0.61) | SMN1; SMN2ALDH1A1HTR1ASLC6A4EBP | |
| SCHEMBL7025832 | 0.74 | EBP (0.43) | ALDH1A1HTR1ASLC6A4EBPSIGMAR1 | |
| SCHEMBL9447564 | 0.72 | ABCB1 (0.45) | ALDH1A1KDM4EHTR1ASLC6A4EBP | |
| SCHEMBL9444495 | 0.72 | KCNH2 (0.58) | SMN1; SMN2ALDH1A1KDM4EHTTABCB1 | |
| Hydrochloric Acid SCHEMBL9444430 | 0.71 | KCNH2 (0.59) | SMN1; SMN2ALDH1A1KDM4EHTTABCB1 | |
| SCHEMBL9027195 | 0.71 | SIGMAR1 (0.54) | SMN1; SMN2ALDH1A1HTR1ASLC6A4EBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0304888-B1 | SULFONAMIDOLPHENYL DERIVATES AND THERAPEUTIC AND PREVENTIVE AGENTS FOR ARRYTHMIA CONTAINING SAME | Eisai Co., Ltd. (JP) | 1992-11-11 | — | — | EP | disclosed |
| EP-0304888-A1 | Sulfonamidolphenyl derivates and therapeutic and preventive agents for arrythmia containing same | Eisai Co., Ltd. (JP) | 1989-03-01 | — | — | EP | disclosed |